Western Blot: OSBPL2 Antibody [NB100-1332] - NB100-1332 staining (1.5 ug/ml) of human heart lysate (RIPA buffer, 30ug total protein per lane). Primary incubated for 1 hour. Detected using chemiluminescence.
Predicted cross-reactivity based on sequence identity: Mouse, Rat.
Alternate Names for OSBPL2 Antibody
OSBP-related protein 2
oxysterol binding protein-like 2
oxysterol-binding protein-like 2
oxysterol-binding protein-related protein 2
This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain, although some members contain only the sterol-binding domain. This encoded protein contains only the sterol-binding domain. In vitro studies have shown that the encoded protein can bind strongly to phosphatic acid and weakly to phosphatidylinositol 3-phosphate, but cannot bind to 25-hydroxycholesterol. The protein associates with the Golgi apparatus. Transcript variants encoding different isoforms have been described.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.