Ornithine Carbamoyltransferase Antibody (OTI8A1) [DyLight 405]

• Reactivity: Hu, Mu, Rt
• Applications: IHC
• Clone: OTI8A1
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: DyLight 405

Ornithine Carbamoyltransferase Antibody (OTI8A1) [DyLight 405] Summary

• Description: This conjugate is made on demand and is not held in inventory. Each order represents a unique lot. All conjugates are generated using validated conjugation protocols and meet strict degree of labeling (F/P) specifications; additional information is available upon request. The antibody concentration is provided on the individual product label.
  
  For specialized conjugation needs, like large quantities, specific concentrations, and defined F/P ratios, bulk and custom antibody conjugation services are available.
• Immunogen: Recombinant protein fragment corresponding to amino acids 33-354 of human Ornithine Carbamoyltransferase (NP_000522)produced in E.coli.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: OTC
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
• Application Notes: Recommended applications are based on validated applications from the unconjugated base product NBP2-73149. This conjugated antibody is not kept in inventory and is made to order using validated conjugation protocols.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for Ornithine Carbamoyltransferase Antibody (OTI8A1) [DyLight 405]

• EC 2.1.3
• EC 2.1.3.3
• MGC129967
• MGC129968
• MGC138856
• OCTD
• Ornithine Carbamoyltransferase
• ornithine carbamoyltransferase, mitochondrial
• Ornithine Transcarbamylase
• OTC
• OTCase

Background

This nuclear gene encodes a mitochondrial matrix enzyme. Missense, nonsense, and frameshift mutations in this enzyme lead to ornithine transcarbamylase deficiency, which causes hyperammonemia. Since the gene for this enzyme maps close to that for Duchenne muscular dystrophy, it may play a role in that disease also. (provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: OTC