OCTN2/SLC22A5 Antibody (893753) [CoraFluor™ 1]

• Reactivity: Hu
• Applications: Flow
• Clone: 893753
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: CoraFluor 1

OCTN2/SLC22A5 Antibody (893753) [CoraFluor™ 1] Summary

• Description: CoraFluor(TM) 1 is a high performance terbium-based TR-FRET (Time-Resolved Fluorescence Resonance Energy Transfer) or TRF (Time-Resolved Fluorescence) donor for high throughput assay development. CoraFluor(IM) 1 absorbs UV light at approximately 340 nm, and emits at approximately 490 nm, 545 nm, 585 nm and 620 nm. It is compatible with common acceptor dyes that absorb at the emission wavelengths of CoraFluor(TM) 1. CoraFluor(TM) 1 can be used for the development of robust and scalable TR-FRET binding assays such as target engagement, ternary complex, protein-protein interaction and protein quantification assays.
• Immunogen: NS0 transfected with human SLC22A5
  Accession # O76082
• Specificity: Detects human OCTN2/SLC22A5 in ELISA.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Mouse
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Flow Cytometry
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark. Do not freeze.
• Buffer: PBS
• Preservative: No Preservative
• Purity: Protein A or G purified

Notes

CoraFluor (TM) is a trademark of Bio-Techne Corp. Sold for research purposes only under agreement from Massachusetts General Hospital. US patent 2022/0025254

Alternate Names for OCTN2/SLC22A5 Antibody (893753) [CoraFluor™ 1]

• CDSP
• FLJ46769
• High-affinity sodium-dependent carnitine cotransporter
• OCTN2
• OCTN2high-affinity sodium dependent carnitine cotransporter
• OCTN2VT
• organic cation transporter 2
• organic cation transporter 5
• Organic cation/carnitine transporter 2
• SCD
• SLC22A5
• solute carrier family 22 (organic cation transporter), member 5
• solute carrier family 22 (organic cation/carnitine transporter), member 5
• solute carrier family 22 member 5

Background

Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. The encoded protein is a plasma integral membrane protein which functions both as an organic cation transporter and as a sodium-dependent high affinity carnitine transporter. The encoded protein is involved in the active cellular uptake of carnitine. Mutations in this gene are the cause of systemic primary carnitine deficiency (CDSP), an autosomal recessive disorder manifested early in life by hypoketotic hypoglycemia and acute metabolic decompensation, and later in life by skeletal myopathy or cardiomyopathy. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.