OCTN2/SLC22A5 Products

Description

Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. The encoded protein is a plasma integral membrane protein which functions both as an organic cation transporter and as a sodium-dependent high affinity carnitine transporter. The encoded protein is involved in the active cellular uptake of carnitine. Mutations in this gene are the cause of systemic primary carnitine deficiency (CDSP), an autosomal recessive disorder manifested early in life by hypoketotic hypoglycemia and acute metabolic decompensation, and later in life by skeletal myopathy or cardiomyopathy. [provided by RefSeq]

Bioinformatics

Entrez	6584 Human
Uniprot	AAH12325.1 Human NM_003060 Human NP_003051 Human
Product By Gene ID	6584
Alternate Names	CDSP FLJ46769 High-affinity sodium-dependent carnitine cotransporter OCTN2high-affinity sodium dependent carnitine cotransporter OCTN2VT organic cation transporter 2 organic cation transporter 5 Organic cation/carnitine transporter 2 SCD solute carrier family 22 (organic cation transporter), member 5 solute carrier family 22 (organic cation/carnitine transporter), member 5 solute carrier family 22 member 5