OCTN2/SLC22A5 Products

Description

Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for the elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. SLC22A5 is an integral plasma membrane protein which functions as an organic cation transporter and as a sodium-dependent high affinity carnitine transporter. Mutations in SLC22A5 are the cause of systemic primary carnitine deficiency (CDSP), an autosomal recessive disorder manifested early in life by hypoketotic hypoglycemia and acute metabolic decompensation, and later in life by skeletal myopathy or cardiomyopathy.

Bioinformatics

Uniprot	O76082 Human
Product By Gene ID	6584
Alternate Names	CDSP FLJ46769 High-affinity sodium-dependent carnitine cotransporter OCTN2 OCTN2high-affinity sodium dependent carnitine cotransporter OCTN2VT organic cation transporter 2 organic cation transporter 5 Organic cation/carnitine transporter 2 SCD SLC22A5 solute carrier family 22 (organic cation transporter), member 5 solute carrier family 22 (organic cation/carnitine transporter), member 5 solute carrier family 22 member 5