OAS2 Antibody (C1) - BSA Free

Western Blot: OAS2 Antibody (C1) [NBP3-41736] - Sample: Recombinant OAS2, Human.

Immunohistochemistry-Paraffin: OAS2 Antibody (C1) [NBP3-41736] - DAB staining on IHC-P; Samples: Human Colon Tissue; Primary Ab: 40ug/ml NBP3-41736; Second Ab: 2ug/mL HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody

• Reactivity: Hu
• Applications: WB
• Clone: C1
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1 mg/ml

OAS2 Antibody (C1) - BSA Free Summary

• Description: Novus Biologicals Mouse OAS2 Antibody (C1) - BSA Free (NBP3-41736) is a monoclonal antibody validated for use in WB. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Immunized with recombinant Human OAS2 (Uniprot#: P29728; Val11-His346 (Uniprot#: P29728)
• Isotype: IgG2b Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: OAS2
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Western Blot 0.01-2ug/mL

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 0.01M PBS, pH7.4, 50% glycerol
• Preservative: 0.05% Proclin 300
• Concentration: 1 mg/ml
• Purity: Protein A or G purified

Alternate Names for OAS2 Antibody (C1) - BSA Free

• (2-5')oligo(A) synthase 2
• (2'-5')oligo(A) synthetase 2
• (2-5')oligo(A) synthetase 2
• 2'5' oligoadenylate synthetase 2
• 2-5A synthase 2
• 2-5A synthetase 2
• 2'-5'-oligoadenylate synthase 2
• 2'-5'-oligoadenylate synthetase 2 (69-71 kD)
• 2'-5'-oligoadenylate synthetase 2, 69/71kDa
• EC 2.7.7
• EC 2.7.7.-
• MGC78578
• OAS2
• p69 OAS / p71 OAS
• p69OAS / p71OAS

Background

OAS2 encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: OAS2