OAS2 Products

Antibodies
OAS2 Antibody (HLS56/3) [Unco ...
OAS2 Antibody (HLS56/3) [Unconjuga...
MAB1925
Species: Hu
Applications: IP, ICC
Host: Mouse Monoclonal
OAS2 Antibody (6E6)
OAS2 Antibody (6E6)
NBP2-46293
Species: Hu
Applications: WB, IHC, IHC-P
Host: Mouse Monoclonal
OAS2 Antibody
OAS2 Antibody
NBP2-58756
Species: Hu
Applications: ICC/IF
Host: Rabbit Polyclonal
Lysates
OAS2 Overexpression Lysate (N ...
OAS2 Overexpression Lysate (Native)
NBL1-13897
Applications: WB
Proteins
Recombinant Human OAS2 Protei ...
Recombinant Human OAS2 Protein
H00004939-P01
Species: Hu
Applications: WB, ELISA, PA
OAS2 Recombinant Protein Anti ...
OAS2 Recombinant Protein Antigen
NBP2-58756PEP
Species: Hu
Applications: AC
RNAi
OAS2 RNAi
OAS2 RNAi
H00004939-R02
Species: Hu
Applications: RNAi, RNAi SP
OAS2 RNAi
OAS2 RNAi
H00004939-R03
Species: Hu
Applications: RNAi, RNAi SP
OAS2 RNAi
OAS2 RNAi
H00004939-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

OAS2 encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq]

Bioinformatics

Uniprot Human
Human
Human
Human
Product By Gene ID 4939
Alternate Names
  • EC 2.7.7
  • (2'-5')oligo(A) synthetase 2
  • EC 2.7.7.-
  • 2'-5'-oligoadenylate synthetase 2 (69-71 kD)
  • MGC78578
  • p69OAS / p71OAS
  • 2-5A synthetase 2
  • p69 OAS / p71 OAS
  • 2'5' oligoadenylate synthetase 2
  • 2-5A synthase 2
  • 2'-5'-oligoadenylate synthase 2
  • (2-5')oligo(A) synthase 2
  • (2-5')oligo(A) synthetase 2
  • 2'-5'-oligoadenylate synthetase 2, 69/71kDa

PTMs for OAS2

Learn more about PTMs related to OAS2.

Phosphorylation
Cleavage
Acetylation
Methylation

Bioinformatics Tool for OAS2

Discover related pathways, diseases and genes to OAS2. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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