Nogo Antibody

Western Blot: Nogo Antibody [NBP1-40279] - Analysis of anti-RTN4 / Nogo antibody with mouse brain tissue lysate at (A) 0.5 and (B) 1 ug/ml.

Immunohistochemistry: Nogo Antibody [NBP1-40279] - Mouse Brain cells with NogoA antibody at 20 ug/mL.

Immunohistochemistry-Paraffin: Nogo Antibody [NBP1-40279] - Analysis of anti-RTN4 / Nogo antibody with human testis at concentration 3 ug/ml.

Product Discontinued

Nogo Antibody Summary

• Immunogen: A 23 amino acid synthetic peptide near the N-terminus of human NogoA. The immunogen is located within the first 50 amino acids of NogoA.
• Epitope: N-Terminus
• Specificity: At least five isoforms of Nogo are known to exist; this antibody is specific for NogoA.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: RTN4
• Purity: Peptide affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100 - 1:2000
  • Immunofluorescence
  • Immunohistochemistry 3 ug/ml
  • Immunohistochemistry-Paraffin 3 ug/ml
  • Western Blot 0.5-1 ug/ml

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.02% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Peptide affinity purified

Alternate Names for Nogo Antibody

• ASY
• foocen
• Human NogoA
• KIAA0886
• My043 protein
• Nbla00271
• Nbla10545
• neurite growth inhibitor 220
• Neurite outgrowth inhibitor
• Neuroendocrine-specific protein C homolog
• Neuroendocrine-specific protein
• NI220/250
• Nogo protein
• NOGO-A
• Nogo-B
• NOGOC
• Nogo-C
• NOGORTN4-B1
• NSP
• NSP-CL
• reticulon 4
• reticulon 5
• reticulon-4
• Reticulon-5
• RTN4-A
• RTN4-B2
• RTN4-C
• RTN-x

Background

Neurite Outgrowth Inhibitor (NOGO) is a myelin associated neurite growth inhibitor found in oligodendrocyte and central nervous system (CNS) myelin membranes of the adult CNS. NOGO plays a role in blocking axonal regeneration in the CNS of higher vertebrates. At least 6 isoforms have been observed arising from alternative splicing. NOGO-A (Isoform 1) is specifically expressed in brain and testes and weakly expressed in heart and skeletal muscle.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: RTN4
• Entrez:
  • 57142(Human)
• Uniprot:
  • Q9NQC3()