NMNAT-2 Antibody (2G8) - Azide and BSA Free

Immunocytochemistry/Immunofluorescence: NMNAT-2 Antibody (2G8) [H00023057-M04] - Analysis of monoclonal antibody to NMNAT2 on HeLa cell. Antibody concentration 10 ug/ml

ELISA: NMNAT-2 Antibody (2G8) [H00023057-M04] - Detection limit for recombinant GST tagged NMNAT2 is 3 ng/ml as a capture antibody.

• Reactivity: Hu, Mu
• Applications: WB, ELISA, ICC/IF
• Clone: 2G8
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: Azide and BSA Free

NMNAT-2 Antibody (2G8) - Azide and BSA Free Summary

• Immunogen: NMNAT2 (AAH20998, 1 a.a. ~ 302 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MEIQELEEIQACQGLWEVFVTLSERARDYLHKTGRFIVIGGIVSPVHDSYGKQGLVSSRHRLIMCQLAVQNSDWIRVDPWECYQDTWQTTCSVLEHHRDLMKRVTGCILSNVNTPSMTPVIGQPQNETPQPIYQNSNVATKPTAAKILGKVGESLSRICCVRPPVERFTFVDENANLGTVMRYEEIELRILLLCGSDLLESFCIPGLWNEADMEVIVGDFGIVVVPRDAADTDRIMNHSSILRKYKNNIMVVKDDINHPMSVVSSTKSRLALQHGDGHVVDYLSQPVIDYILKSQLYINASG
• Specificity: Reacts with nicotinamide nucleotide adenylyltransferase 2.
• Isotype: IgG2b Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: NMNAT2
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
  • Immunocytochemistry/ Immunofluorescence 1:10-1:500
  • Western Blot
• Application Notes: This antibody is reactive against recombinant protein in ELISA.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: In 1x PBS, pH 7.4
• Preservative: No Preservative
• Purity: Protein A purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for NMNAT-2 Antibody (2G8) - Azide and BSA Free

• C1orf15
• chromosome 1 open reading frame 15
• EC 2.7.7.1
• EC 2.7.7.18
• KIAA0479MGC2756
• NaMN adenylyltransferase 2
• nicotinamide mononucleotide adenylyltransferase 2
• nicotinamide nucleotide adenylyltransferase 2
• Nicotinate-nucleotide adenylyltransferase 2
• NMN adenylyltransferase 2
• NMNAT2
• NMNAT-2
• PNAT2
• pyridine nucleotide adenylyltransferase 2

Background

This gene product belongs to the nicotinamide mononucleotide adenylyltransferase (NMNAT) enzyme family, members of which catalyze an essential step in NAD (NADP) biosynthetic pathway. Unlike the other human family member, which is localized to the nucleus, and is ubiquitously expressed; this enzyme is cytoplasmic, and is predominantly expressed in the brain. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for NMNAT-2 Antibody (H00023057-M04)(1)

Publication using H00023057-M04

• Ali YO, Bradley G, Lu HC. Screening with an NMNAT2-MSD platform identifies small molecules that modulate NMNAT2 levels in cortical neurons. Sci Rep 2017-03-07 [PMID: 28266613]

Bioinformatics

• Gene Symbol: NMNAT2
• Entrez:
  • 23057(Human)
• Uniprot:
  • AAH20998(Human)