NIPP1 Antibody Pair

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Summary
Product Discontinued
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    • Catalog Number
      H00005511-PW1
    • Availability
      Product Discontinued

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NIPP1 Antibody Pair Summary

Description
Quality control test: Immunoprecipitation-Western Blot (IP-WB). This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.

  • Antibody pair for IP: mouse monoclonal anti-PPP1R8 (300 ug)
  • Antibody pair for WB: mouse monoclonal anti-PPP1R8 (50 ug)
  • Clonality
    Polyclonal
    Gene
    PPP1R8
    Purity
    Immunogen affinity purified

    Applications/Dilutions

    Dilutions
    • Immunoprecipitation
    • Western Blot

    Packaging, Storage & Formulations

    Storage
    Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
    Buffer
    1x PBS, pH 7.4
    Preservative
    No Preservative
    Purity
    Immunogen affinity purified

    Notes

    This product is produced by and distributed for Abnova, a company based in Taiwan.

    Alternate Names for NIPP1 Antibody Pair

    • activator of RNA decay
    • ARD1
    • ard-1
    • ARD1nuclear inhibitor of protein phosphatase 1
    • NIPP1
    • NIPP1nuclear inhibitor of protein phosphatase-1
    • NIPP-1nuclear subunit of PP-1
    • PPP1R8
    • PRO2047
    • Protein phosphatase 1 regulatory inhibitor subunit 8
    • protein phosphatase 1 regulatory subunit 8
    • protein phosphatase 1, regulatory (inhibitor) subunit 8
    • RNase E

    Background

    NIPP1, through alternative splicing, encodes three different isoforms. Two of the protein isoforms encoded by this gene are specific inhibitors of type 1 serine/threonine protein phosphatases and can bind but not cleave RNA. The third protein isoform lacks the phosphatase inhibitory function but is a single-strand endoribonuclease comparable to RNase E of E. coli. This isoform requires magnesium for its function and cleaves specific sites in A+U-rich regions of RNA.

    Limitations

    This product is for research use only and is not approved for use in humans or in clinical diagnosis. Antibody Pairs are guaranteed for 6 months from date of receipt.

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    H00005511-PW1
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    Product General Protocols

    Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

    Video Protocols

    WB Video Protocol

    FAQs for NIPP1 Antibody Pair (H00005511-PW1). (Showing 1 - 1 of 1 FAQ).

    1. Could I get information about the isotypes of the two antibodies included in this set and the dilutions for using in IP?
      • Antibody pair for IP: mouse monoclonal anti-PPP1R8 (300 ug): isotype: IgG2a Kappa

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    Bioinformatics

    Gene Symbol PPP1R8