Nidogen-2 Antibody (JF6)

Product Discontinued

Nidogen-2 Antibody (JF6) Summary

• Immunogen: Recombinant fragment corresponding to the G1 region of mouse nidogen.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Rat
• Gene: NID2
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
  • Western Blot 1:500-1:2000
• Application Notes: Western Blot: Recognizes native and denatured nidogen. This antibody is able to block the binding of nidogen to laminin.

Reactivity Notes

Human, Mouse

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: 20mM Phosphate (pH 7.6) and 0.25M NaCl
• Preservative: 0.1% Sodium Azide
• Purity: Protein A or G purified

Notes

Relevant Entrez Gene Numbers: NM_002508.2

Alternate Names for Nidogen-2 Antibody (JF6)

• NID2
• NID-2
• nidogen 2 (osteonidogen)
• Nidogen2
• Nidogen-2
• Osteonidogen

Background

Basement membranes, which are composed of type IV collagens (see MIM 120130), laminins (see LAMC1; MIM 150290), perlecan (HSPG2; MIM 142461), and nidogen (see NID1; MIM 131390), are thin pericellular protein matrices that control a large number of cellular activities, including adhesion, migration, differentiation, gene expression, and apoptosis.[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: NID2
• Uniprot:
  • P14543(Human)