Recombinant Human Neurokinin B Protein

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SDS-Page: Neurokinin B Protein [NBP1-30196] - Neurokinin B, 13.8 kDa (125aa), confirmed by MALDI-TOF with a purity of 95% by SDS - PAGE

Product Details

Summary
Reactivity HuSpecies Glossary
Applications PAGE
Concentration
0.5 mg/ml

Order Details

Recombinant Human Neurokinin B Protein Summary

Description
A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 17-121 of Human Neurokinin B

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH QSFGAVCKEP QEEVVPGGGR SKRDPDLYQL LQRLFKSHSS LEGLLKALSQ ASTDPKESTS PEKRDMHDFF VGLMGKRSVQ PDSPTDVNQE NVPSFGILKY PPRAE

Source
E. coli
Protein/Peptide Type
Recombinant Protein
Gene
TAC3
Purity
>95% pure by SDS-PAGE

Applications/Dilutions

Theoretical MW
13.8 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
20 mM Tris-HCl buffer (pH 8.0) containing 20% glycerol
Preservative
No Preservative
Concentration
0.5 mg/ml
Purity
>95% pure by SDS-PAGE

Alternate Names for Recombinant Human Neurokinin B Protein

  • gamma tachykinin 3
  • neurokinin beta
  • neurokinin B-like
  • neuromedin K
  • preprotachykinin B
  • PRO1155
  • tachykinin 3
  • tachykinin-3
  • ZNEUROK1NKNBNKB

Background

Neurokinin B, a member of the substance P-related tachykinin family, was previously known to be present in the same hypothalamic neurons as kisspeptin. This protein and its receptor are critical switches of regulator of human puberty, governed by the brain through the release of the hormone GnRH (gonadotropin-releasing hormone) which starts a series of processes that ultimately leads to the production of sex hormones. Many studies suggest new approaches to the pharmacological control of human reproduction and sex hormone-related diseases. Recombinant human Neurokinin B, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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Bioinformatics

Gene Symbol TAC3