Human Neurokinin B ELISA Kit (Colorimetric)

ELISA: Human Neurokinin B ELISA Kit (Colorimetric) [NBP2-76743] - Samples were spiked with high concentrations of Human Neurokinin B and diluted with Reference Standard & Sample Diluent to produce samples with values within the range of the assay.

ELISA: Human Neurokinin B ELISA Kit (Colorimetric) [NBP2-76743] - Standard Curve Reference

• Reactivity: Hu
• Applications: ELISA
• Suitable Sample Type: Serum, plasma and other biological fluids
• Standard Curve Range: 15.625 - 1000pg/mL
• Sensitivity: 9.375pg/mL

Human Neurokinin B ELISA Kit (Colorimetric) Summary

• Standard Curve Range: 15.625 - 1000pg/mL
• Sensitivity: 9.375pg/mL
• Assay Type: Competitive-ELISA
• Inter-Assay: CV% < 5.38
• Intra-Assay: CV% < 4.66
• Spike Recovery: 90-111%
• Sample Volume: 50 uL
• Kit Type: ELISA Kit (Colorimetric)
• Gene: TAC3

Applications/Dilutions

• Dilutions:
  • ELISA

Packaging, Storage & Formulations

• Storage: Storage of components varies. See protocol for specific instructions.

Alternate Names for Human Neurokinin B ELISA Kit (Colorimetric)

• gamma tachykinin 3
• neurokinin beta
• neurokinin B-like
• neuromedin K
• preprotachykinin B
• PRO1155
• tachykinin 3
• tachykinin-3
• ZNEUROK1NKNBNKB

Background

The Neurokinins, also known as Tachykinins, belong to an evolutionary conserved family of peptide neurotransmitters that share a c-terminal sequence and have an established role in neurotransmission. The mammalian tachykinins include substance P (NK1), neurokinin A (NKA) and neurokinin B (NKB) which exert their effects by binding to specific receptors. Tachykinin peptides are important in the mediation of many physiological and pathological processes including inflammation, pain, migraine headache and allergy induced asthma.

Three tachykinin receptor types have been characterized, NK-1, NK-2 and NK-3 which have preferential affinities for SP, NKA and NKB respectively. All three receptors share a high degree of sequence homology, have seven transmembrane spanning domains and similar signal transduction mechanisms (e.g. G-protein coupled activation of phospholipase C).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are guaranteed for 6 months from date of receipt.

Publications for Neurokinin B ELISA Kit (NBP2-76743)(1)

Publication using NBP2-76743

• Zhang L, Fernando T, Liu Y et al. Neurokinin 3 receptor antagonist-induced adipocyte activation improves obesity and metabolism in PCOS-like mice Life sciences 2022-10-14 [PMID: 36252700] (ELISA)

Bioinformatics

• Gene Symbol: TAC3