Neurofibromin 1 Antibody (CL11773) - BSA Free

Staining of U-2 OS cells using the Anti-NF1 monoclonal antibody, showing specific staining in nucleoplasm in green. Microtubule probe is visualized in red.

• Reactivity: Hu, Mu, Rt
• Applications: ICC/IF
• Clone: CL11773
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: BSA Free

Neurofibromin 1 Antibody (CL11773) - BSA Free Summary

• Immunogen: This antibody was developed using a synthetic peptide derived from P21359, with the exact immunogen sequence remaining proprietary.
• Predicted Species: Mouse (100%), Rat (100%). Backed by our 100% Guarantee.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Gene: NF1
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence 2-10 ug/ml
• Application Notes: ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS, pH 7.2, 40% glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Protein A purified

Alternate Names for Neurofibromin 1 Antibody (CL11773) - BSA Free

• DKFZp686J1293
• FLJ21220
• Neurofibromatosis-related protein NF-1
• neurofibromin 1
• neurofibromin
• NFNS
• VRNF
• WSS

Background

Neurofibromin 1 (NF1) is a suspected negative regulator of the ras signal transduction pathway. Neurofibromin is known to regulate the GTPase HRAS, causing the hydrolyzation and inactivation of GTP. Defects in NF1 lead to Neurofibromatosis disease, Recklinghausen disease or Watson disease. Neurofibromin has not been purified, therefore, most of the information regarding this protein has been deduced from homology analysis of its gene sequence.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: NF1