Neuregulin-1 beta 1/NRG1 beta 1 Antibody (147705) [Alexa Fluor™ Plus 680]

• Reactivity: Hu
• Clone: 147705
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor Plus 680

Neuregulin-1 beta 1/NRG1 beta 1 Antibody (147705) [Alexa Fluor™ Plus 680] Summary

• Specificity: Detects human NRG1-beta 1 in ELISAs. Recognizes an epitope found in the EGF-like domain of NRG1‑ beta 1 (amino acids 179‑246). It also detects recombinant human SMDF (Sensory and Motor neuron-Derived Factor), but it does not recognize the EGF-like domain of human NRG1-alpha (amino acids 177‑241). The epitope is present within amino acids 213‑230 of human NRG1-beta 1. This segment is present in all NRG1 beta isoforms, GGF‑2 (glial growth factor), and SMDF, but it is absent from NRG1-alpha , NDF43, and NRG1-gamma .
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Neuregulin-1 beta 1/NRG1 beta 1 Antibody (147705) [Alexa Fluor™ Plus 680]

• ARIA
• GGF
• GGF2
• HGL
• HRG
• HRG1
• HRGA
• MST131
• MSTP131
• NDF
• neuregulin 1
• Neuregulin1 beta 1
• Neuregulin-1 beta 1
• NRG1-IT2
• SMDF

Background

Neuregulin-1, also known as Heregulin 1, functions as a ligand for the receptor tyrosine kinases, ErbB3 and ErbB4. It exists in several different mRNA splicing variants resulting in both transmembrane and secreted forms.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.