NDFIP1 Antibody [Alexa Fluor® 488]

• Reactivity: Hu, Mu, Rt
• Applications: WB, ICC/IF
• Clonality: Polyclonal
• Host: Sheep
• Conjugate: Alexa Fluor 488

NDFIP1 Antibody [Alexa Fluor® 488] Summary

• Immunogen: E. coli-derived recombinant human NDFIP1
  Ala10-Asp105
  Accession # Q9BT67
• Specificity: Detects human, mouse and rat NDFIP1 in Western blots.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Sheep
• Purity Statement: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for NDFIP1 Antibody [Alexa Fluor® 488]

• Breast cancer-associated protein SGA-1M
• MGC10924
• N4WBP5
• N4WBP5Putative NF-kappa-B-activating protein 164
• NDFIP1
• Nedd4 family interacting protein 1
• NEDD4 family-interacting protein 1
• NEDD4 WW domain-binding protein 5
• Putative MAPK-activating protein PM13
• Putative NFKB and MAPK-activating protein

Background

NDFIP1 (NEDD4 family-interacting protein 1 and NEDD4 WW domain-binding protein 5) is a 26 kDa widely expressed protein. NDFIP1 is thought to be part of a family of integral Golgi membrane proteins. It serves as an adaptor for several E3 ubiquitin ligases including NEDD4 and ITCH, and consequently modulates the stability of their targets. NDFIP1 is genetically linked to human allergic and autoimmune disease, but the cellular mechanism by which these proteins enable foreign and self-antigens to be tolerated is unresolved. Over aa10-105, human NDFIP1 is 95% identical to mouse and rat NDFIP1.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.