Myosin light chain 3 Antibody (7C1)

Western Blot: Myosin light chain 3 Antibody (7C1) [NBP1-51569] - Western blot analysis using MYL3 (1) and MYL2 (2) mouse mAb against rat fetal heart tissues lysate.

Immunohistochemistry-Paraffin: Myosin light chain 3 Antibody (7C1) [NBP1-51569] - Immunohistochemical analysis of paraffin-embedded human Heart tissues using MYL3 mouse mAb.

Immunohistochemistry-Paraffin: Myosin light chain 3 Antibody (7C1) [NBP1-51569] - Immunohistochemical analysis of paraffin-embedded human skeletal muscle (left) and cardiac muscle (right) using MYL3 mouse mAb with DAB staining.

Product Discontinued

Myosin light chain 3 Antibody (7C1) Summary

• Immunogen: Purified recombinant fragment of MYL3 expressed in E. Coli.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: MYL3
• Purity: Unpurified

Applications/Dilutions

• Dilutions:
  • ELISA 1:10000
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:200-1:1000
  • Western Blot 1:500-1:2000
• Theoretical MW: 22 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: Ascites
• Preservative: 0.03% Sodium Azide
• Purity: Unpurified

Alternate Names for Myosin light chain 3 Antibody (7C1)

• Cardiac myosin light chain 1
• CMH8Ventricular/slow twitch myosin alkali light chain
• CMLC1
• light polypeptide 3, alkali; ventricular, skeletal, slow
• MLC1SBMyosin light chain 1, slow-twitch muscle B/ventricular isoform
• MLC1V
• myosin light chain 3
• myosin, light chain 3, alkali; ventricular, skeletal, slow
• VLC1

Background

MYL3 encodes myosin light chain 3, an alkali light chain also referred to in the literature as both the ventricular isoform and the slow skeletal muscle isoform. Mutations in MYL3 have been identified as a cause of mid-left ventricular chamber type hypertrophic cardiomyopathy. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Myosin light chain 3 Antibody (NBP1-51569)(1)

Publication using NBP1-51569

• Su YR, Chiusa M, Brittain E et al. Right ventricular protein expression profile in end-stage heart failure. Pulm Circ 2015-09-01 [PMID: 26401249] (WB)

Bioinformatics

• Gene Symbol: MYL3