Myosin 1C Antibody

Western Blot: Myosin 1C Antibody [NBP2-19454] - Sample (30 ug of whole cell lysate) A: Non-transfected 293T lysates B: MYO1C transfected 293T lysate 5% SDS PAGE gel, diluted at 1:5000.

Immunohistochemistry-Paraffin: Myosin 1C Antibody [NBP2-19454] - Immunohistochemical analysis of paraffin-embedded PC14 xenograft, using antibody at 1:500 dilution.

Western Blot: Myosin 1C Antibody [NBP2-19454] - Sample (30 ug of whole cell lysate) A: A431 5% SDS PAGE gel, diluted at 1:1000.

Product Discontinued

Myosin 1C Antibody Summary

• Immunogen: Recombinant protein encompassing a sequence within the N-terminus region of human Myosin 1C. The exact sequence is proprietary.
• Localization: Cytoplasm; Cell membrane (By similarity); Cell projection; stereocilium membrane (By similarity); Isoform 3: Nucleus; nucleoplasm; Nucleus; nucleolus; nuclear pore complex
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: MYO1C
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 10 - 1:500
  • Immunohistochemistry-Paraffin 1:100-1:1000
  • Western Blot 1:1000-1:10000
• Theoretical MW: 118 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7), 20% Glycerol
• Preservative: 0.01% Thimerosal
• Purity: Immunogen affinity purified

Alternate Names for Myosin 1C Antibody

• FLJ23903
• MMIb
• MMI-beta
• Myosin I beta
• myosin IC
• myosin-I beta
• myosin-Ic
• myr2
• NMI
• nuclear myosin I

Background

This gene encodes a member of the unconventional myosin protein family, which are actin-based molecular motors. The protein is found in the cytoplasm, and one isoform with a unique N-terminus is also found in the nucleus. The nuclear isoform associates with RNA polymerase I and II and functions in transcription initiation. The mouse ortholog of this protein also functions in intracellular vesicle transport to the plasma membrane. Multiple transcript variants encoding different isoforms have been found for this gene. The related gene myosin IE has been referred to as myosin IC in the literature, but it is a distinct locus on chromosome 19. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

Bioinformatics

• Gene Symbol: MYO1C