Myoglobin Antibody (7C3)

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications S-ELISA
Clone
7C3
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

Myoglobin Antibody (7C3) Summary

Immunogen
Human cardiac myoglobin
Localization
Cytoplasmic
Specificity
Human cardiac myoglobin
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
MB
Purity
Protein A purified
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Applications/Dilutions

Dilutions
  • Sandwich ELISA 1:100-1:2000
Application Notes
Recommended pairs for sandwich immunoassay (capture-detection): NB600-1291 - NB120-8345

Reactivity Notes

Not yet tested in other species.

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
PBS (pH 7.4)
Preservative
0.09% Sodium Azide
Purity
Protein A purified

Alternate Names for Myoglobin Antibody (7C3)

  • MB
  • MGC13548
  • Myoglobin
  • PVALB

Background

Myoglobin is a small heme containing protein (153 amino acid residues, molecular weight (w/o heme) 17053 Da and theoretical pI=7.29) responsible for the oxygen deposition in muscle tissues. Only one form of myoglobin is expressed in cardiac and skeletal muscles. Myoglobin is known as a marker of myocardial damage and it has been used for more than three decades. Nowadays it still is very commonly used in clinical practice as an early marker of AMI. It appears in patient's blood 1 to 3 hours after onset of the symptoms, reaching peak level within 8 to 12 hours. Myoglobin is not so cardiac specific as cTnI or cTnT. Because of high myoglobin concentration in skeletal muscle tissue, even minor skeletal muscle injury results in the significant increase of myoglobin concentration in blood. Thus myoglobin is used together with cTnI or cTnT in clinical practise for better specificity in AMI diagnosis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol MB
Entrez
Uniprot