Myoferlin Antibody - BSA Free

Immunohistochemistry: Myoferlin Antibody - BSA Free [NBP3-46963] - Immunohistochemistry of paraffin-embedded human placenta using (Myoferlin antibody) at dilution of 1:100

Western Blot: Myoferlin Antibody - BSA Free [NBP3-46963] - A549 cells were subjected to SDS PAGE followed by western blot with (Myoferlin antibody) at dilution of 1:300

• Reactivity: Hu
• Applications: WB, ELISA, ICC/IF, IHC, NULL
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

Myoferlin Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit Myoferlin Antibody - BSA Free (NBP3-46963) is a polyclonal antibody validated for use in IHC, WB, ELISA and ICC/IF. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: myoferlin. (Uniprot# Q9NZM1)
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: MYOF
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunocytochemistry/ Immunofluorescence 1:20-1:200
  • Immunohistochemistry 1:20-1:200
  • Serum FC
  • Western Blot 1:500-1:2000
• Theoretical MW: 235 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS, 50% Glycerol, pH (7.3)
• Preservative: 0.02% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for Myoferlin Antibody - BSA Free

• fer-1 (C.elegans)-like 3 (myoferlin)
• FER1L3
• fer-1-like 3, myoferlin (C. elegans)
• fer-1-like 3, myoferlin
• Fer-1-like protein 3
• FLJ36571
• FLJ90777
• KIAA1207
• myoferlin

Background

Myoferlin belongs to the ferlin family and contains five C2 domains. It is a calcium/phospholipid binding protein that plays a role in the plasmalemma repair mechanism of endothelial cells that permits rapid resealing of membranes disrupted by mechanical stress. It is also involved in endocytic recycling and implicated in VEGF signal transduction by regulating the levels of the receptor KDR. Myoferlin is expressed in myoblast and endothelial cells (at protein level), highly expressed in cardiac and skeletal muscles, also present in lung and at very low levels in kidney, placenta and brain. There are eight named isoforms.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: MYOF