MYO6 Antibody

• Reactivity: Hu, Po
• Applications: WB
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated

MYO6 Antibody Summary

• Immunogen: Full lengthmyosin-6 construct expressed in SF9 insect cells corresponding to porcine myosyn-6 protein.
• Clonality: Polyclonal
• Host: Rabbit
• Gene: MYO6
• Purity: Delipidation and Defibrination

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: This antibody has been tested by western blot. For western blots expect a band of approximately 150 kDa in size corresponding to full length and ~85kDa and ~60kDa for truncated myosin-6 protein. Specific conditions for reactivity should be optimized by the end user. This antibody is suitable for use in ELISA.

Reactivity Notes

BLAST analysis was used to suggest reactivity with 94% human Myosin VI. Cross-reactivity with myosin6 from other sources have not been determined.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
• Preservative: 0.01% Sodium Azide
• Purity: Delipidation and Defibrination

Alternate Names for MYO6 Antibody

• DFNA22
• DFNB37
• KIAA0389deafness, autosomal recessive 37
• myosin VI
• myosin-VI
• Unconventional myosin-6

Background

MYO6 encodes a protein involved intracellular vesicle and organelle transport, especially in the hair cell of the inner ear. Mutations in this gene have been found in patients with non-syndromic autosomal dominant and recessive hearing loss. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: MYO6