MVP Antibody (1032) [DyLight 405]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, ICC/IF, IHC, IHC-P
Clone
1032
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 405

Order Details

MVP Antibody (1032) [DyLight 405] Summary

Immunogen
proteins precipitated from human breast cancer MCF-7 cells
Localization
Cytoplasmic
Specificity
Recognizes a protein of 104kDa-110kDa, characterized as major vault protein (MVP). Vaults are large ribonucleoprotein particles (RNPs) present in all eukaryotic cells. They have a complex morphology, including several small molecules of RNA, but a single protein species. The MVP accounts for >70% of their mass. Their shape is reminiscent of the nucleopore central plug. Treatment of cells with estradiol increases the amount of MVP in nuclear extract. The hormone-dependent interaction of vaults with ER is prevented in vitro by sodium molybdate. Antibodies to estrogen, progesterone and glucocorticoid receptors are able to co-immunoprecipitate the MVP. MVP is overexpressed in many neoplastic tissues and cell lines. Expression of MVP predicts a poor response to chemotherapy.
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
MVP
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry
  • Immunocytochemistry/Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes

Dylight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for MVP Antibody (1032) [DyLight 405]

  • LRPVAULT1
  • Lung resistance-related protein
  • major vault protein

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

ICC/IF Video Protocol

FAQs for MVP Antibody (NBP2-47807V). (Showing 1 - 1 of 1 FAQ).

  1. Are there any MVP antibodies that will recognize mouse and can be used for immunofluorescence?
    • At this time we do not have an MVP antibody that will recognize mouse and has been used for immunofluorescence. If you would like to try an antibody in an untested species or application you would qualify for our Innovator's Reward program. Through this program if you complete an online review with image, detailing your positive or negative results we will send you a discount voucher for 100% of the purchase price of the reviewed product.

Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 350 NBP2-47807AF350
Alexa Fluor 405 NBP2-47807AF405
Alexa Fluor 488 NBP2-47807AF488
Alexa Fluor 532 NBP2-47807AF532
Alexa Fluor 594 NBP2-47807AF594
Alexa Fluor 647 NBP2-47807AF647
Alexa Fluor 700 NBP2-47807AF700
Alexa Fluor 750 NBP2-47807AF750
Allophycocyanin NBP2-47807APC
Biotin NBP2-47807B
DyLight 350 NBP2-47807UV
DyLight 405 NBP2-47807V
DyLight 488 NBP2-47807G
DyLight 550 NBP2-47807R
DyLight 594 NBP2-47807DL594
DyLight 650 NBP2-47807C
DyLight 680 NBP2-47807FR
DyLight 755 NBP2-47807IR
FITC NBP2-47807F
HRP NBP2-47807H
Janelia Fluor 549 NBP2-47807JF549
Janelia Fluor 646 NBP2-47807JF646
PE NBP2-47807PE
PerCP NBP2-47807PCP

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Calculators

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Bioinformatics

Gene Symbol MVP