Muscarinic Acetylcholine Receptor M1/CHRM1 Antibody

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Western Blot: Muscarinic Acetylcholine Receptor M1/CHRM1 Antibody [NB100-41399] - Staining of mouse heart lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Product Details

Summary
Reactivity MuSpecies Glossary
Applications WB, PEP-ELISA
Clonality
Polyclonal
Host
Goat
Conjugate
Unconjugated
Concentration
0.5 mg/ml

Order Details

Muscarinic Acetylcholine Receptor M1/CHRM1 Antibody Summary

Immunogen
Peptide with sequence C-DKRRWRKIPKRPGSVH corresponding to C-Terminus according to NP_000729.2.
Isotype
IgG
Clonality
Polyclonal
Host
Goat
Gene
CHRM1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 0.3 - 1 ug/ml
  • Peptide ELISA Detection limit 1:64000
Application Notes
WB: Approx 50 kDa band observed in mouse heart lysates (calculated MW of 51.4 kDa according to NP_000729.2).
Positive Control
Muscarinic Acetylcholine Receptor M1/CHRM1 Lysate (NBL1-09173)
Publications
Read Publications using
NB100-41399 in the following applications:

  • WB
    1 publication

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Human, Rat, Canine.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
0.5 mg/ml Tris (pH 7.3) and 0.5% BSA
Preservative
0.02% Sodium Azide
Concentration
0.5 mg/ml
Purity
Immunogen affinity purified

Alternate Names for Muscarinic Acetylcholine Receptor M1/CHRM1 Antibody

  • cholinergic receptor, muscarinic 1
  • CHRM1
  • HM1
  • M1
  • M1R
  • mAChR M1
  • MGC30125
  • muscarinic acetylcholine receptor M1

Background

The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 1 is involved in mediation of vagally-induced bronchoconstriction and in the acid secretion of the gastrointestinal tract. The gene encoding this receptor is localized to 11q13.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Muscarinic Acetylcholine Receptor M1/CHRM1 Antibody (NB100-41399)(2)

We have publications tested in 1 confirmed species: Rat.

We have publications tested in 1 application: WB.


Filter By Application
WB
(1)
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(1)
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Positive Control Lysate(s)

Secondary Antibodies

 

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Bioinformatics

Gene Symbol CHRM1
Entrez
Uniprot