Western Blot: Muscarinic Acetylcholine Receptor M1/CHRM1 Antibody [NB100-41399] - (0.3ug/ml) staining of Mouse Heart lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Western Blot: Muscarinic Acetylcholine Receptor M1/CHRM1 Antibody [NB100-41399] - (1ug/ml) staining of Human Brain lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Predicted cross-reactivity based on sequence identity: Mouse, Rat, Canine.
Alternate Names for Muscarinic Acetylcholine Receptor M1/CHRM1 Antibody
cholinergic receptor, muscarinic 1
muscarinic acetylcholine receptor M1
The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 1 is involved in mediation of vagally-induced bronchoconstriction and in the acid secretion of the gastrointestinal tract. The gene encoding this receptor is localized to 11q13.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.