Musashi-2 Antibody [Biotin] Summary
E. coli-derived recombinant human Musashi-2 isoform 1
Accession # Q96DH6
Detects human Musashi-2 in Western blots. In Western blots, approximately 15% cross-reactivity with recombinant human Musashi-1 is observed.
Test in a species/application not listed above to receive a full credit towards a future purchase.
Packaging, Storage & Formulations
|Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.
Reconstitute at 0.2 mg/mL in sterile PBS.
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for Musashi-2 Antibody [Biotin]
- musashi homolog 2 (Drosophila)
- RNA-binding protein Musashi homolog 2
Musashi-2 belongs to the evolutionarily conserved Musashi family of RNA
binding proteins which are involved in the translational control of
their target mRNAs. Musashi-2 has two tandem RNA-recognition domains
(RRM-1 and RRM-2) that have the highly conserved RNP
(ribonucleoprotein) motifs. By alternative splicing, at least three
Musashi-2 isoforms exist. In mammalian nervous system, Musashi-1 and –2
are selectively expressed in neural progenitor cells and play important
roles in maintenance of the stem cell fate. Human Musashi-2 shares 95%
amino acid sequence homology with mouse Musashi-2 and 80% amino acid
sequence identity with human Musashi-1. Translocations resulting in the
formation of Musashi-2/HOXA9 fusion protein is associated with
progression of chronic myelogenous leukemia to the accelerated phase
and blast crisis.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed
for 1 year from date of receipt.
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