MUL1 Antibody

Product Discontinued

MUL1 Antibody Summary

• Immunogen: Recombinant protein encompassing a sequence within the center region of human MUL1. The exact sequence is proprietary.
• Localization: Mitochondrion outer membrane; Multi-pass membrane protein; Peroxisome
• Predicted Species: Mouse (90%), Rat (91%), Rhesus Macaque (100%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: MUL1
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence 1:100-1:1000
  • Immunohistochemistry 1:100-1:1000
  • Immunohistochemistry-Paraffin 1:100-1:1000
  • Western Blot 1:500-1:3000
• Theoretical MW: 40 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Bovine (82%)

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7), 20% Glycerol
• Preservative: 0.025% Proclin 300
• Purity: Immunogen affinity purified

Alternate Names for MUL1 Antibody

• C1orf166mitochondrial E3 ubiquitin ligase 1
• E3 ubiquitin-protein ligase MUL1
• EC 6.3.2
• EC 6.3.2.-
• FLJ12875
• GIDERP11-401M16.2
• Growth inhibition and death E3 ligase
• MAPLE3 ubiquitin ligase
• mitochondrial E3 ubiquitin protein ligase 1
• mitochondrial ubiquitin ligase activator of NFKB 1
• mitochondrial ubiquitin ligase activator of NF-kB
• Mitochondrial-anchored protein ligase
• MULANchromosome 1 open reading frame 166
• Putative NF-kappa-B-activating protein 266
• RING finger protein 218
• RNF218mitochondria-anchored protein ligase

Background

E3 ubiquitin-protein ligase that plays a role in the control of mitochondrial morphology. Promotes mitochondrial fragmentation and influences mitochondrial localization. Inhibits cell growth. When overexpressed, activates JNK through MAP3K7/TAK1 and induces caspase-dependent apoptosis. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: MUL1