MST3 Antibody

Western Blot: MST3 Antibody [NB100-1582] - Detection of Human MST3(STK24) on HeLa whole cell lysate.

• Reactivity: Hu
• Applications: WB, IP
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Concentration: 0.2 mg/ml

MST3 Antibody Summary

• Immunogen: The immunogen recognized by this antibody maps to a region between residues 325 and 375 of human Mammalian Ste20-like Kinase 3 (Serine/Threonine Kinase 24) using the numbering given in entry NP_003567.2 (GeneID 8428).
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: STK24
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation 1-4 ug/mg of lysate
  • Western Blot 1:1000-1:10000

Packaging, Storage & Formulations

• Storage: Store at 4C. Do not freeze.
• Buffer: TBS and 0.1% BSA
• Preservative: 0.09% Sodium Azide
• Concentration: 0.2 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for MST3 Antibody

• EC 2.7.11
• EC 2.7.11.1
• Mammalian STE20-like protein kinase 3
• MST-3
• MST3serine/threonine kinase 24 (Ste20, yeast homolog)
• serine/threonine kinase 24
• serine/threonine-protein kinase 24
• STE20
• STE20-like kinase 3
• STE20-like kinase MST3
• sterile 20-like kinase 3
• STK3yeast)

Background

MST3/STK24 is a member of the sterile 20 (Ste20)-like kinase family that acts upstream of mitogen-activated protein kinase (MAPK) pathways and regulates c-Jun N-terminal kinase (JNK), p38 and extracellular signal-regulated kinase (ERK). Ste20-like kinases are involved in a variety of cellular processes which include gene transcription, stress responses, cytoskeletal organization and apoptosis. In response to apoptotic signals, MST3/STK24 is cleaved by caspase-3 and mediates apoptosis. The biological functions of MST3/STK24 are not well understood. Alternate names for MST3/STK24 include serine/threonine-protein kinase 24, STE20-like protein kinase 3, STK3, MST-3 and MST3B.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for MST3 Antibody (NB100-1582)(2)

Publications using NB100-1582

• Zalvide J, AlmenglO C, VAzquez S et al. Measuring the Kinase Activity of GCKIII Proteins In Vitro Methods Mol. Biol. 2020-06-12 [PMID: 32524571]
• Mitidieri E, Tramontano T, Gurgone D, Citi V. Mercaptopyruvate acts as endogenous vasodilator independently of 3-mercaptopyruvate sulfurtransferase activity. Nitric Oxide. 2018-02-13 [PMID: 29452248] (WB)

Bioinformatics

• Gene Symbol: STK24
• Entrez:
  • 8428(Human)
• Uniprot:
  • NP_003567.2(Human)