MST3 Products

Antibodies
MST3 Antibody
MST3 Antibody
NBP1-87833
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
MST3 Antibody
MST3 Antibody
NBP1-87834
Species: Hu, Mu, Rt, Mouse, Rat
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
MST3 Antibody
MST3 Antibody
NBP1-31360
Species: Hu, Rt, Bovine, Chicken, Mouse, Xenopus, Monkey
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
MST3 Overexpression Lysate (N ...
MST3 Overexpression Lysate (Native)
NBP2-10596
Applications: WB
Proteins
MST3 Recombinant Protein Anti ...
MST3 Recombinant Protein Antigen
NBP1-87834PEP
Species: Hu
Applications: AC
MST3 Recombinant Protein Anti ...
MST3 Recombinant Protein Antigen
NBP1-87833PEP
Species: Hu
Applications: AC
MST3 Recombinant Protein
MST3 Recombinant Protein
P3924
Species: Hu
Applications: Func, PAGE
RNAi
MST3 RNAi
MST3 RNAi
H00008428-R02
Species: Hu

Description

The growth of axons is fundamental to the development and repair of brain circuitry. It has been shown that Mst3, a neuron-specific homolog of the yeast kinase Ste20, is critical for axon outgrowth. Mst3 is activated in response to trophic factors, and suppressing its expression or its function blocks axon outgrowth (1). Mst3 has been recently demonstrated to undergo a caspase-mediated cleavage during apoptosis. The proteolytic cleavage of the C-terminus of Mst3 caused nuclear translocation of its kinase domain. Mst3 contains both nuclear localization sequence (NLS) and NES signals, which may cooperate to control the subcellular distribution of Mst3 (2). In situ hybridization of rat brain sections indicated that MST3b is widely expressed in different brain regions, with especially high expression in hippocampus and cerebral cortex. When expressed in human embryonic kidney 293 (HEK293) cells, MST3b effectively phosphorylated myelin basic protein, as well as undergoing autophosphorylation (3)

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Human
Product By Gene ID 8428
Alternate Names
  • EC 2.7.11
  • STE20-like kinase MST3
  • sterile 20-like kinase 3
  • Mammalian STE20-like protein kinase 3
  • STE20-like kinase 3
  • MST-3
  • serine/threonine-protein kinase 24
  • STE20
  • STK3yeast)
  • MST3serine/threonine kinase 24 (Ste20, yeast homolog)
  • EC 2.7.11.1
  • serine/threonine kinase 24

Research Areas for MST3

Find related products by research area and learn more about each of the different research areas below.

Protein Kinase

PTMs for MST3

Learn more about PTMs related to MST3.

Phosphorylation
Cleavage
Dephosphorylation

Bioinformatics Tool for MST3

Discover related pathways, diseases and genes to MST3. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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