MSK1/RPS6KA5 Antibody (252608) [Alexa Fluor® 405]

• Applications: ICC/IF
• Clone: 252608
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 405

MSK1/RPS6KA5 Antibody (252608) [Alexa Fluor® 405] Summary

• Immunogen: E. coli-derived recombinant human MSK1
  Met1-Ala802
  Accession # O75582
• Specificity: Detects human MSK1 but not human MSK2 in direct ELISAs.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Background

Mitogen- and stress-activated protein kinase 1 (MSK1), also known as 90 kDa ribosomal protein S6 kinase 5 (RPS6KA5), belongs to the AGC family of kinases. Both MSK1 and the related MSK2 have two kinase domains connected by a regulatory linker region and are activated by the mitogen-activated protein kinases ERK1, ERK2, and p38. Nuclear MSK phosphorylates and activates a number of transcription factors, including ATF1 and CREB.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.