MSK1/RPS6KA5 Products

Antibodies
MSK1/RPS6KA5 Antibody [Unconj ...
MSK1/RPS6KA5 Antibody [Unconjugated]
AF2518
Species: Hu, Mu
Applications: WB, ICC
Host: Goat Polyclonal
MSK1/RPS6KA5 [p Ser212] Antib ...
MSK1/RPS6KA5 [p Ser212] Antibody
AF1036
Species: Hu
Applications: WB, IHC
Host: Rabbit Polyclonal
MSK1/RPS6KA5 Antibody (252608 ...
MSK1/RPS6KA5 Antibody (252608)
MAB2518
Species: Hu
Applications: ICC
Host: Mouse Monoclonal
Antibody Pairs
MSK1/RPS6KA5 Antibody Pair
MSK1/RPS6KA5 Antibody Pair
H00009252-AP11
Species: Hu
Applications: S-ELISA
Lysates
MSK1/RPS6KA5 Overexpression L ...
MSK1/RPS6KA5 Overexpression Lysate...
NBP2-07829
Applications: WB
MSK1/RPS6KA5 Overexpression L ...
MSK1/RPS6KA5 Overexpression Lysate...
NBP2-09810
Applications: WB
MSK1/RPS6KA5 Overexpression L ...
MSK1/RPS6KA5 Overexpression Lysate...
NBL1-15572
Applications: WB
Proteins
MSK1/RPS6KA5 Recombinant Prot ...
MSK1/RPS6KA5 Recombinant Protein
H00009252-P01
Species: Hu
Applications: WB, ELISA, PA, PAGE, KA
MSK1/RPS6KA5 Partial Recombin ...
MSK1/RPS6KA5 Partial Recombinant P...
H00009252-Q02
Species: Hu
Applications: WB, ELISA, PA
MSK1/RPS6KA5 Partial Recombin ...
MSK1/RPS6KA5 Partial Recombinant P...
H00009252-Q01
Species: Hu
Applications: WB, ELISA, PA
RNAi
MSK1/RPS6KA5 RNAi
MSK1/RPS6KA5 RNAi
H00009252-R05
Species: Hu
MSK1/RPS6KA5 RNAi
MSK1/RPS6KA5 RNAi
H00009252-R06
Species: Hu

Description

MSK-1 is a mitogen and stress activated protein kinase-1 which belongs to the AGC family of kinases and is related in structure to the ribosomal p70 S6 kinase subfamily. MSK-1can be activated by ERK1/2 and SAPK2 /p38 MAP kinase. It is also known to be required for the phosphorylation of CREB, ATF1 H3 and HMG-14 in response to mitogen and stress (1-2). Similar to RSK, MSK-1 contains two kinase domains (N-term and a C-term) (3). Once phosphorylated on Thr581 and Ser360 by ERK1/2 and SAPK2/p38, MSK-1 autophosphorylate on at least 5 sites. Of these autophosphorylation sites Ser212 and Ser376 get phosphorylated by the C-terminal kinase domain of MSK-1 which is essential for the catalytic activity of the N-terminal kinase domain (4).

Bioinformatics

Entrez Human
Mouse
Uniprot Human
Human
Human
Human
Human
Human
Product By Gene ID 9252
Alternate Names
  • EC 2.7.11
  • S6K-alpha-5
  • ribosomal protein S6 kinase alpha-5
  • RSKL
  • MSPK1
  • MGC1911,90 kDa ribosomal protein S6 kinase 5
  • Nuclear mitogen- and stress-activated protein kinase 1
  • ribosomal protein S6 kinase, 90kD, polypeptide 5
  • RLPK
  • MSK1EC 2.7.11.1
  • RSK-like protein kinase
  • ribosomal protein S6 kinase, 90kDa, polypeptide 5

Diseases related to MSK1/RPS6KA5

Discover more about diseases related to MSK1/RPS6KA5.

Horse Diseases
Chronic Respiratory Disease
Neurotoxicity Syndromes
Respiration Disorders
Airway Obstruction
Coffin-lowry Syndrome

Pathways for MSK1/RPS6KA5

View related products by pathway and learn more about each of the pathways below.

Sensitization
Chromatin Remodeling

Research Areas for MSK1/RPS6KA5

Find related products by research area and learn more about each of the different research areas below.

Phospho-Specific
Protein Kinase
Signal Transduction

PTMs for MSK1/RPS6KA5

Learn more about PTMs related to MSK1/RPS6KA5.

Phosphorylation
Acetylation

Bioinformatics Tool for MSK1/RPS6KA5

Discover related pathways, diseases and genes to MSK1/RPS6KA5. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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