Mouse CCL8/MCP-2 DuoSet ELISA, 15 Plate

• Reactivity: Mu
• Applications: ELISA
• Conjugate: Biotin

Mouse CCL8/MCP-2 DuoSet ELISA, 15 Plate Summary

• Source: N/A
• Assay Type: Solid Phase Sandwich ELISA
• Inter-Assay: See PDF Datasheet for details
• Intra-Assay: See PDF Datasheet for details
• Spike Recovery: See PDF Datasheet for details
• Sample Volume: See PDF Datasheet for details
• Gene: Ccl8

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: No significant interference observed with available related molecules.

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Mouse CCL8/MCP-2 DuoSet ELISA, 15 Plate

• C-C motif chemokine 8
• CCL8
• chemokine (C-C motif) ligand 8
• HC14
• MCP2
• MCP-2
• member 8 (monocyte chemotactic protein 2)
• monocyte chemoattractant protein 2
• SCYA10
• small-inducible cytokine A8

Background

MCP-2 is a CC chemokine subfamily monocyte chemotactic protein. MCP-2 also chemoattracts activated NK cells, CD4+ and CD8+ T lymphocytes, and eosinophils and can induce histamine secretion from basophils. MCP-2 shares 62% amino acid sequence identity with MCP-1 and 58% with MCP-3.

Publications for CCL8/MCP-2 (DY790)(11)

Publications using DY790

• Sha, L;Li, J;Shen, H;Wang, Q;Meng, P;Zhang, X;Deng, Y;Zhu, W;Xu, Q; LHPP-mediated inorganic pyrophosphate hydrolysis-driven lysosomal acidification in astrocytes regulates adult neurogenesis Cell reports 2023-08-11 [PMID: 37573508] (Mouse)
• Kim, HS;Lee, HK;Kim, K;Ahn, GB;Kim, MS;Lee, TY;Son, DJ;Kim, Y;Hong, JT;Han, SB; Mesenchymal stem cells enhance CCL8 expression by podocytes in lupus-prone MRL.Faslpr mice Scientific reports 2023-08-11 [PMID: 37567910] (Transgenic Mouse)
• F Honda, H Tsuboi, Y Ono, S Abe, H Takahashi, K Ito, K Yamada, M Kawano, Y Kondo, K Asano, M Tanaka, M Malissen, B Malissen, I Matsumoto, T Sumida Pathogenic roles and therapeutic potential of the CCL8-CCR8 axis in a murine model of IgG4-related sialadenitis Arthritis Research & Therapy, 2021-08-14;23(1):214. 2021-08-14 [PMID: 34391459] (Mouse)
• PLD Silva, F Lauretti-F, M Caldas de, SS Lima, AE Covarrubia, M De Franco, E Carvalho, PL Ho, RMA da Costa, EAL Martins, JB Da Silva Phagocytosis of Leptospira by leukocytes from mice with different susceptibility to leptospirosis and possible role of chemokines BMC Microbiol., 2019-01-07;19(1):4. 2019-01-07 [PMID: 30616505] (Mouse)
• Elena Farmaki Induction of the MCP chemokine cluster cascade in the periphery by cancer cell-derived CCL3 Cancer Lett, 2016-12-29;0(0):. 2016-12-29 [PMID: 28041977] (Mouse)
• A CCL8 gradient drives breast cancer cell dissemination Oncogene, 2016-05-16;0(0):. 2016-05-16 [PMID: 27181207] (Mouse)
• Ottina E, Lyberg K, Sochalska M, Villunger A, Nilsson G Knockdown of the antiapoptotic Bcl-2 family member A1/Bfl-1 protects mice from anaphylaxis. J Immunol, 2014-12-29;194(3):1316-22. 2014-12-29 [PMID: 25548219] (Mouse)
• Dulek D, Newcomb D, Goleniewska K, Cephus J, Zhou W, Reiss S, Toki S, Ye F, Zaynagetdinov R, Sherrill T, Blackwell T, Moore M, Boyd K, Kolls J, Peebles R Allergic airway inflammation decreases lung bacterial burden following acute Klebsiella pneumoniae infection in a neutrophil- and CCL8-dependent manner. Infect Immun, 2014-06-23;82(9):3723-39. 2014-06-23 [PMID: 24958709] (Mouse)
• Gaffal E, Jakobs M, Glodde N, Schroder R, Kostenis E, Tuting T beta-arrestin 2 inhibits proinflammatory chemokine production and attenuates contact allergic inflammation in the skin. J Invest Dermatol, 2014-02-27;134(8):2131-7. 2014-02-27 [PMID: 24577407] (Mouse)
• Gaffal E, Cron M, Glodde N, Bald T, Kuner R, Zimmer A, Lutz B, Tuting T Cannabinoid 1 receptors in keratinocytes modulate proinflammatory chemokine secretion and attenuate contact allergic inflammation. J Immunol, 2013-04-12;190(10):4929-36. 2013-04-12 [PMID: 23585676] (Mouse)
• Pitteri SJ, Kelly-Spratt KS, Gurley KE Tumor microenvironment-derived proteins dominate the plasma proteome response during breast cancer induction and progression. Cancer Res., 2011-06-08;71(15):5090-100. 2011-06-08 [PMID: 21653680] (Mouse)

Bioinformatics

• Gene Symbol: Ccl8