MMP-7 Antibody (704202) [Alexa Fluor™ Plus 405]

• Reactivity: Mu
• Clone: 704202
• Clonality: Monoclonal
• Host: Rat
• Conjugate: Alexa Fluor Plus 405

MMP-7 Antibody (704202) [Alexa Fluor™ Plus 405] Summary

• Specificity: Detects mouse MMP-7 in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human MMP-7, recombinant mouse (rm) MMP‑3, or rmMMP-8 is observed.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Rat

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for MMP-7 Antibody (704202) [Alexa Fluor™ Plus 405]

• EC 3.4.24
• EC 3.4.24.23
• Matrilysin
• matrin
• matrix metallopeptidase 7 (matrilysin, uterine)
• matrix metalloproteinase 7 (matrilysin, uterine)
• Matrix metalloproteinase-7
• MMP7
• MMP-7
• MPSL1
• Pump-1 protease
• PUMP1
• PUMP-1
• uterine matrilysin
• Uterine metalloproteinase

Background

MMP-7 (Matrilysin, 28 kDa) is the smallest member of the matrix metalloproteinases (MMP) family. It is expressed by normal and abnormal epithelial cells and is capable of digesting many proteins of the extracellular matrix.  MMP-7 is implicated in the activation of Plasminogen, FasL, intestinal alpha-Defensin (important in innate host defense), and MMPs-1, -2, and -9, and in the release of TNF-alpha.  Mouse MMP-7 is synthesized with a signal peptide and a propeptide; the preproMMP-7 shows 87% and 70% aa identity with rat and human preproMMP-7, respectively.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.