MMP-25/MT6-MMP Antibody (141825) [Alexa Fluor® 700]

• Reactivity: Hu
• Applications: WB, IHC
• Clone: 141825
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 700

MMP-25/MT6-MMP Antibody (141825) [Alexa Fluor® 700] Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant human MMP‑25
  Pro314-Cys508
  Accession # Q9NPA2
• Specificity: Detects human MMP‑25/MT6-MMP Hemopexin Domain in Western blots. It recognizes E. coli-expressed hemopexin domain and
  NS0‑expressed recombinant human MMP-25.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for MMP-25/MT6-MMP Antibody (141825) [Alexa Fluor® 700]

• Leukolysin
• matrix metallopeptidase 25
• matrix metallopeptidase-like 1
• matrix metalloproteinase 20
• matrix metalloproteinase 25
• matrix metalloproteinase-25
• matrix metalloproteinase-like 1
• membrane-type 6 matrix metalloproteinase
• membrane-type matrix metalloproteinase 6
• membrane-type-6 matrix metalloproteinase
• MMP20
• MMP20A
• MMP25
• MMP-25
• MMPL1
• MT6MMP
• MT6-MMP
• MT-MMP 6
• MTMMP6
• MT-MMP6

Background

Matrix Metalloproteinase 25 (MMP-25), also known as MT6-MMP or Leukolysin, is a GPI-linked protease expressed by neutrophils. The extracellular domain of MMP-25 consists of a pro region, a catalytic domain and a hemopexin domain. MMP-25 cleaves collagen type 4, gelatin, fibronectin and fibrin.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.