MMP-25/MT6-MMP Products

Antibodies
MMP-25/MT6-MMP Antibody (1418 ...
MMP-25/MT6-MMP Antibody (141825)
MAB11421
Species: Hu
Applications: WB, IHC
Host: Mouse Monoclonal
MMP-25/MT6-MMP Antibody (1418 ...
MMP-25/MT6-MMP Antibody (141808) [...
MAB1142
Species: Hu
Applications: WB, Flow
Host: Mouse Monoclonal
MMP-25/MT6-MMP Antibody (1418 ...
MMP-25/MT6-MMP Antibody (141811) [...
MAB11422
Species: Hu
Applications: ICFlow
Host: Mouse Monoclonal
RNAi
MMP-25/MT6-MMP RNAi
MMP-25/MT6-MMP RNAi
H00064386-R01
Species: Hu
Applications: RNAi, RNAi SP
MMP-25/MT6-MMP RNAi
MMP-25/MT6-MMP RNAi
H00064386-R02
Species: Hu
Applications: RNAi, RNAi SP

Description

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling. They are also involved in disease processes, such as metastasis and arthritis. Most MMPs are secreted as inactive proproteins which are then activated when cleaved by extracellular proteinases. The protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily, and is attached to the plasma membrane via a glycosylphosphatidyl inositol anchor. The encoded protein is thought to inactivate alpha-1 proteinase inhibitor, a major tissue protectant against proteolytic enzymes released by activated neutrophils, facilitating the transendothelial migration of neutrophils to inflammatory sites in response to bacterial infection or inflammation. The encoded protein may also play a role in tumor invasion and metastasis through activation of MMP2. The gene has previously been referred to as MMP20 but has been renamed MMP25.

Bioinformatics

Entrez Human
Uniprot Human
Product By Gene ID 64386
Alternate Names
  • MMPL1
  • matrix metalloproteinase-like 1
  • MT6-MMP
  • membrane-type matrix metalloproteinase 6
  • MT-MMP 6
  • MT-MMP6
  • MMP20
  • membrane-type 6 matrix metalloproteinase
  • MMP20A
  • matrix metallopeptidase-like 1
  • matrix metalloproteinase 25
  • matrix metalloproteinase-25
  • MT6MMP
  • leukolysin
  • matrix metalloproteinase 20
  • membrane-type-6 matrix metalloproteinase
  • MMP-25
  • MTMMP6
  • matrix metallopeptidase 25

Research Areas for MMP-25/MT6-MMP

Find related products by research area and learn more about each of the different research areas below.

Angiogenesis
Cancer

PTMs for MMP-25/MT6-MMP

Learn more about PTMs related to MMP-25/MT6-MMP.

Cleavage
Reduction
Methylation

Bioinformatics Tool for MMP-25/MT6-MMP

Discover related pathways, diseases and genes to MMP-25/MT6-MMP. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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