Meis homeobox 3 Antibody (OTI3E12) [mFluor Violet 500 SE]

Meis homeobox 3 Antibody (OTI3E12) [mFluor Violet 500 SE] - Vial of mFluor Violet 500 conjugated antibody. mFluor Violet 500 is optimally excited at 410 nm by the Violet laser (405 nm) and has an emission maximum of 501 nm.

• Reactivity: Hu, Mu, Rt
• Applications: WB, Flow, IHC
• Clone: OTI3E12
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: mFluor Violet 500 SE

Meis homeobox 3 Antibody (OTI3E12) [mFluor Violet 500 SE] Summary

• Immunogen: Human recombinant protein fragment corresponding to amino acids 1-261 of human MEIS3 (NP_064545) produced in E.coli.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: MEIS3
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Flow Cytometry
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Mouse-On-Mouse blocking reagent may be needed for IHC and ICC experiments to reduce high background signal. You can find these reagents under catalog numbers PK-2200-NB and MP-2400-NB. Please contact Technical Support if you have any questions.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for Meis homeobox 3 Antibody (OTI3E12) [mFluor Violet 500 SE]

• DKFZp547H236
• Meis homeobox 3
• Meis1, myeloid ecotropic viral integration site 1 homolog 3 (mouse)
• Meis1, myeloid ecotropic viral integration site 1 homolog 3
• Meis1-related protein 2
• MRG2homeobox protein Meis3

Background

MEIS3, also known as Homeobox protein Meis3, has 3 isoforms, a 375 amino acid isoform that is 41 kDa, a 421 amino acid isoform that is 46 kDa, and a 358 amino acid isoform that is 39 kDa, and is nucleus located. Little is currently known about its function. Studies are performed on the relationship of this protein to neuronitis. MEIS3 protein involvement has been observed with relation to HOXA13 in the regulation of transcription, DNA-dependent, negative regulation of apoptotic process, and positive regulation of protein kinase B signaling cascade pathways.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: MEIS3