MED7 Antibody (PCRP-MED7-1B8) [Alexa Fluor™ Plus 405]

Product Discontinued

MED7 Antibody (PCRP-MED7-1B8) [Alexa Fluor™ Plus 405] Summary

• Immunogen: Recombinant full-length human MED7 protein (Uniprot: O43513)
• Localization: Nucleus, Nuclear bodies
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Gene: MED7
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Flow Cytometry
  • Immunocytochemistry/ Immunofluorescence
  • Immunoprecipitation
  • Protein Array
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified

Notes

This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is conditioned on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not (1) use this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; or (c) manufacturing or quality assurance or quality control, and/or (2) sell or transfer this product or its components for resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for MED7 Antibody (PCRP-MED7-1B8) [Alexa Fluor™ Plus 405]

• Activator-recruited cofactor 34 kDa component
• Cofactor required for Sp1 transcriptional activation subunit 9
• cofactor required for Sp1 transcriptional activation, subunit 9 (33kD)
• cofactor required for Sp1 transcriptional activation, subunit 9, 33kDa
• CRSP33CRSP complex subunit 9
• CRSP9hMED7
• mediator complex subunit 7ARC34
• mediator of RNA polymerase II transcription subunit 7
• MGC12284
• RNA polymerase transcriptional regulation mediator subunit 7 homolog
• Transcriptional coactivator CRSP33

Background

The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. Two transcript variants encoding the same protein have been found for this gene.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: MED7