Recombinant Human MATH1 Protein

SDS-Page: Recombinant Human MATH1 Protein [NBP1-99040] - 15% SDS-PAGE (3ug)

• Reactivity: Hu
• Applications: PAGE
• Concentration: 1 mg/ml

Recombinant Human MATH1 Protein Summary

• Description: An un-tagged denatured recombinant protein corresponding to the amino acids 158-354 of Human MATH1
  
  

  Source: E.coli

  Amino Acid Sequence: MKQRRLAANA RERRRMHGLN HAFDQLRNVI PSFNNDKKLS KYETLQMAQI YINALSELLQ TPSGGEQPPP PPASCKSDHH HLRTAASYEG GAGNATAAGA QQASGGSQRP TPPGSCRTRF SAPASAGGYS VQLDALHFST FEDSALTAMM AQKNLSPSLP GSILQPVQEE NSKTSPRSHR SDGEFSPHSH YSDSDEAS

• Source: E. coli
• Protein/Peptide Type: Recombinant Protein
• Gene: ATOH1
• Purity: >85%, by SDS-PAGE

Applications/Dilutions

• Dilutions:
  • SDS-Page
• Theoretical MW: 21.3 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 20 mM Tris-HCl buffer (pH8.0), 10% glycerol, 0.4M UREA
• Preservative: No Preservative
• Concentration: 1 mg/ml
• Purity: >85%, by SDS-PAGE

Alternate Names for Recombinant Human MATH1 Protein

• ATH1protein atonal homolog 1
• atonal homolog 1 (Drosophila)
• BHLHA14
• bHLHa14Math1
• Class A basic helix-loop-helix protein 14
• HATH1
• Helix-loop-helix protein hATH-1
• MATH-1

Background

ATOH1, also known as protein atonal homolog 1, activates E box-dependent transcription in collaboration with TCF3/E47, but the activity is completely antagonized by the negative regulator of neurogenesis HES1. This protein may play a role in the differentiation of subsets of neural cells by activating E box-dependent transcription. Recombinant human ATOH1 protein, fused to His-tag at N-terminus, was expressed in E.coli.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Bioinformatics

• Gene Symbol: ATOH1