MAML3 Antibody (MAML3/1303)

Immunohistochemistry-Paraffin: MAML3 Antibody (MAML3/1303) [NBP2-47646] - Formalin-fixed, paraffin-embedded Human Placenta stained with MAML3 Monoclonal Antibody (MAML3/1303).

Immunohistochemistry-Paraffin: MAML3 Antibody (MAML3/1303) [NBP2-47646] - Formalin-fixed, paraffin-embedded Human Pancreas stained with MAML3 Monoclonal Antibody (MAML3/1303).

Immunohistochemistry-Paraffin: MAML3 Antibody (MAML3/1303) [NBP2-47646] - Formalin-fixed, paraffin-embedded Human Colon Carcinoma stained with MAML3 Monoclonal Antibody (MAML3/1303).

Immunohistochemistry-Paraffin: MAML3 Antibody (MAML3/1303) [NBP2-47646] - Formalin-fixed, paraffin-embedded Human Cervical Carcinoma stained with MAML3 Monoclonal Antibody (MAML3/1303).

• Reactivity: Hu
• Applications: IHC
• Clone: MAML3/1303
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Concentration: 0.2 mg/ml

MAML3 Antibody (MAML3/1303) Summary

• Description: 200ug/ml of antibody purified from Bioreactor Concentrate by Protein A or G. Prepared in 10 mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0 mg/ml. (NBP2-54309)
  
  Antibody with azide - store at 2 to 8C. Antibody without azide - store at -20 to -80C.
• Immunogen: Recombinant human MAML3 protein fragment (Uniprot: Q96JK9)
• Localization: Cytoplasmic
• Isotype: IgG1 Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: MAML3
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 1-2 ug/ml
• Application Notes: Immunohistochemistry (Formalin-fixed): 1-2ug/ml for 30 minutes at RT. Staining of formalin-fixed tissues is enhanced by heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0 for 45 min at 95C followed by cooling at RT for 20 minutes.
  Optimal dilution for a specific application should be determined.

Packaging, Storage & Formulations

• Storage: Store at 4C.
• Buffer: 10 mM PBS with 0.05% BSA
• Preservative: 0.05% Sodium Azide
• Concentration: 0.2 mg/ml
• Purity: Protein A or G purified

Alternate Names for MAML3 Antibody (MAML3/1303)

• CAG/CTG 3
• ERDA3
• MAM-2
• mam-3
• mastermind-like 3 (Drosophila)
• mastermind-like protein 3
• polyglutamine rich
• trinucleotide repeat containing 3

Background

There are 3 MAML (mastermind-like) proteins in mammals (MAML1-3). MAML3 is a coactivator for NOTCH signaling. MAML3 associates with NOTCH and CSL in a ternary complex and functions to activate transcription of HES and hairy-related basic helix-loop-helix transcription factors.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: MAML3
• Uniprot:
  • Q96JK9(Human)