LYPD8 Antibody (961703) [Alexa Fluor™ Plus 680]

• Reactivity: Hu
• Clone: 961703
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor Plus 680

LYPD8 Antibody (961703) [Alexa Fluor™ Plus 680] Summary

• Specificity: Detects human LYPD8 in direct ELISAs. Stains human LYPD8 transfectants but not irrelevant transfectants in flow cytometry.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for LYPD8 Antibody (961703) [Alexa Fluor™ Plus 680]

• LYPD8

Background

Ly6/PLAUR domain containing 8 (LYPD8), is a GPI-linked protein with structural similarity to the urokinase-type plasminogen activator receptor (uPAR) (1). Mature human LYPD8 contains one uPAR/Ly6 domain and a Ser/Thr/Pro-rich (STP) region that may serve as a target for protease mediated shedding as has been shown for the related C4.4A/LYPD3 molecule (2, 3). Mature human LYPD8 shares 40% amino acid sequence identity with mouse and rat LYPD8.

1. Kong, H.K. and J.H. Park (2012) BMB Rep. 45:595.
2. Hansen, L.V. et al. (2004) Biochem. J. 380:845.
3. Esselens, C.W. et al. (2008) Biol. Chem. 389:1075.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.