Lnx1 Antibody (OTI1H9) [Janelia Fluor® 635]

Product Discontinued

Lnx1 Antibody (OTI1H9) [Janelia Fluor® 635] Summary

• Immunogen: Human recombinant protein fragment corresponding to amino acids 260-528 of human LNX1 (NP_116011) produced in E.coli.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: LNX1
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for Lnx1 Antibody (OTI1H9) [Janelia Fluor® 635]

• EC 6.3.2.-
• ligand of numb-protein X 1ligand of numb-protein X
• LNXmulti-PDZ-domain-containing protein, E3 ubiquitin-protein ligase LNX
• MPDZ
• Numb-binding protein 1
• PDZ domain-containing ring finger protein 2
• PDZRN2E3 ubiquitin-protein ligase LNX

Background

Lnx1 encodes a membrane-bound protein that is involved in signal transduction and protein interactions. The encoded product is an E3 ubiquitin-protein ligase, which mediates ubiquitination and subsequent proteasomal degradation of proteins containing phosphotyrosine binding (PTB) domains. This protein may play an important role in tumorogenesis. Alternatively spliced transcript variants encoding distinct isoforms have been described. A pseudogene, which is located on chromosome 17, has been identified for this gene. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: LNX1