LMAN1 Antibody (1H6) [Alexa Fluor® 488]

• Reactivity: Hu, Mu
• Applications: WB, ELISA, ICC/IF
• Clone: 1H6
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 488

LMAN1 Antibody (1H6) [Alexa Fluor® 488] Summary

• Immunogen: Mouse monoclonal LMAN1 antibody was raised against a 19 amino acid peptide near the carboxy terminus of human LMAN1.
• Specificity: At least two isoforms of LMAN1 are known to exist.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: LMAN1
• Purity: Peptide affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunocytochemistry/ Immunofluorescence
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Peptide affinity purified

Notes

Alexa Fluor (R) products are provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@lifetech.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for LMAN1 Antibody (1H6) [Alexa Fluor® 488]

• ERGIC-53
• ERGIC53ER-Golgi intermediate compartment 53 kDa protein
• F5F8Dendoplasmic reticulum-golgi intermediate compartment protein 53
• FMFD1
• Gp58
• intracellular mannose specific lectin
• Intracellular mannose-specific lectin MR60
• Lectin mannose-binding 1
• lectin, mannose-binding, 1
• MCFD1coagulation factor V-factor VIII combined deficiency
• MR60
• protein ERGIC-53

Background

Protein trafficking along the endoplasmic reticulum (ER) to the Golgi apparatus occurs by vesicular transport between membranous compartments. LMAN1 is a mannose-specific lectin transport receptor protein which cycles between the ER and the Golgi complex. LMAN1 is involved in intracellular transport of many glycoproteins. LMAN1 is useful in studying mechanisms underlying protein trafficking early in the secretory pathway.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: LMAN1