LIV-1/Zip6 Antibody [ADC] - (Ladiratuzumab Vedotin, Research Grade)

Human LIV1 CHOS cells were stained with LIV-1/Zip6 (Ladiratuzumab Vedotin) Antibody and negative control protein respectively, washed and then followed by PE and analyzed with FACS, EC50=0.07456 ug/mL.

The killing ratio LIV-1/Zip6 (Ladiratuzumab Vedotin) Antibody by Human LIV-1 HEK293 Cell Line increased with the increase of antibody concentration, and the killing Rate (%) reached 74%

Immobilized human LIV 1, His Tag at 2 ug/mL can bind LIV-1/Zip6 (Ladiratuzumab Vedotin) Antibody, EC50=0.007652 ug/mL.

• Reactivity: Hu
• Applications: ELISA, Flow, Func
• Clonality: Monoclonal
• Host: Human
• Conjugate: ADC
• Concentration: LYOPH

LIV-1/Zip6 Antibody [ADC] - (Ladiratuzumab Vedotin, Research Grade) Summary

• Description: This product is an Antibody-Drug Conjugate (ADC) for Research Use Only (RUO).
  
  Ladiratuzumab Vedotin is an ADC that combines a humanized anti-LIV-1 monoclonal antibody linked to a synthetic cytotoxic cell-disrupting agent, monomethyl auristatin E (MMAE)
  
  This product is shipped at ambient temperature. Upon receipt, store immediately at -20C or lower for 12 months in a lyophilized state. - 80C for 3 months after reconstitution. Avoid repeated freeze-thaw cycles.
• Immunogen: LIV-1/Zip6 (Uniprot: Q13433)
• Source: CHO
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Human
• Purity: > 90% by SDS-PAGE and HPLC

Applications/Dilutions

• Dilutions:
  • ELISA
  • Flow Cytometry
  • Functional
• Theoretical MW: 146.96 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at -20C in powder form. Store at -80C once reconstituted.
• Buffer: Lyophilized from 25mM histidine, 8% sucrose, 0.01% Tween80 (pH6.2)
• Preservative: No Preservative
• Concentration: LYOPH
• Purity: > 90% by SDS-PAGE and HPLC
• Reconstitution Instructions: Reconstitute with sterile, distilled water to a final concentration of 1 mg/ml. Gently shake to solubilize completely. Do not vortex.

Alternate Names for LIV-1/Zip6 Antibody [ADC] - (Ladiratuzumab Vedotin, Research Grade)

• zinc transporter ZIP6
• LIV-1
• solute carrier family 39 (zinc transporter), member 6

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.