LH beta Antibody (LHb/1214) [Allophycocyanin]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow
Clone
LHb/1214
Clonality
Monoclonal
Host
Mouse
Conjugate
Allophycocyanin

Order Details

LH beta Antibody (LHb/1214) [Allophycocyanin] Summary

Immunogen
Recombinant beta sub-unit of human LH
Localization
Cytoplasmic, secreted
Specificity
Luteinizing hormone (LH) is a glycoprotein. Each monomeric unit is a sugar-like protein molecule; two of these make the full, functional protein. Its structure is similar to the other glycoproteins, follicle-stimulating hormone (FSH), thyroid-stimulating hormone (TSH), and human chorionic gonadotropin (hCG). The protein dimer contains 2 polypeptide units, labeled alpha and beta subunits that are connected by two bridges. The alpha subunits of LH, FSH, TSH, and hCG are identical, and contain 92 amino acids. The beta subunits vary. LH has a beta subunit of 121 amino acids (LHB) that confers its specific biologic action and is responsible for interaction with the LH receptor. This beta subunit contains the same amino acids in sequence as the beta subunit of hCG and both stimulate the same receptor; however, the hCG beta subunit contains an additional 24 amino acids and the hormones differ in the composition of their sugar moieties.LH is synthesized and secreted by gonadotrophs in the anterior lobe of the pituitary gland. In concert with the other pituitary gonadotropin follicle-stimulating hormone (FSH), it is necessary for proper reproductive function. In the female, an acute rise of LH levels triggers ovulation. In the male, where LH has also been called Interstitial Cell-Stimulating Hormone (ICSH), it stimulates Leydig cell production of testosterone. LH is a useful marker in classification of pituitary tumors and the study of pituitary disease.
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
LHB
Purity
Protein A or G purified
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Applications/Dilutions

Dilutions
  • Flow Cytometry
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes

This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for LH beta Antibody (LHb/1214) [Allophycocyanin]

  • CGB4
  • hLHB
  • interstitial cell stimulating hormone, beta chain
  • LH beta
  • LHB
  • LSH-B
  • LSH-beta
  • luteinizing hormone beta polypeptide
  • luteinizing hormone beta subunit
  • lutropin beta chain
  • Lutropin beta
  • lutropin subunit beta

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 350 NBP2-47733AF350
Alexa Fluor 405 NBP2-47733AF405
Alexa Fluor 488 NBP2-47733AF488
Alexa Fluor 532 NBP2-47733AF532
Alexa Fluor 594 NBP2-47733AF594
Alexa Fluor 647 NBP2-47733AF647
Alexa Fluor 700 NBP2-47733AF700
Alexa Fluor 750 NBP2-47733AF750
Allophycocyanin NBP2-47733APC
Biotin NBP2-47733B
DyLight 350 NBP2-47733UV
DyLight 405 NBP2-47733V
DyLight 488 NBP2-47733G
DyLight 550 NBP2-47733R
DyLight 594 NBP2-47733DL594
DyLight 650 NBP2-47733C
DyLight 680 NBP2-47733FR
DyLight 755 NBP2-47733IR
FITC NBP2-47733F
HRP NBP2-47733H
Janelia Fluor 549 NBP2-47733JF549
Janelia Fluor 646 NBP2-47733JF646
PE NBP2-47733PE
PerCP NBP2-47733PCP

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Contact Information

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Calculators

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Bioinformatics

Gene Symbol LHB