LC3C 293T Cell Transient Overexpression Lysate

Product Discontinued

LC3C 293T Cell Transient Overexpression Lysate Summary

• Description: Quality control test: Transient overexpression cell lysate was tested with Anti-MAP1LC3C antibody by Western Blots. Plasmid: pCMV-MAP1LC3C full-length
• Specificity: LC3C 293T Cell Transient Overexpression Lysate(Denatured)
• Gene: MAP1LC3C

Applications/Dilutions

• Dilutions:
  • Western Blot

Packaging, Storage & Formulations

• Storage: Store at -80C. Avoid freeze-thaw cycles.
• Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)

Lysate Details for Array

• Type: 293T Cell Transient Overexpression
• Protein State: Denatured

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for LC3C 293T Cell Transient Overexpression Lysate

• ATG8J
• Autophagy-related protein LC3 C
• Autophagy-related ubiquitin-like modifier LC3 C
• LC3C
• LC3-like protein 2
• MAP1 light chain 3-like protein 2
• MAP1 light chain 3-like protein 3
• MAP1A/MAP1B LC3 C
• microtubule-associated protein 1 light chain 3 gammaMAP1A/MAP1B light chain 3 C
• microtubule-associated proteins 1A/1B light chain 3C

Background

FUNCTION: Probably involved in formation of autophagosomal vacuoles (autophagosomes). SUBUNIT: 3 different light chains, LC1, LC2 and LC3, can associate with MAP1A and MAP1B proteins. SUBCELLULAR LOCATION: LC3-I: Cytoplasm. LC3-II: Intracytoplasmic membrane; lipid-anchor. LC3-II binds to the autophagic membranes. TISSUE SPECIFICITY: Most abundant in placenta, lung and ovary. PTM: The precursor molecule is cleaved by APG4B/ATG4B to form the cytosolic form, LC3-I. This is activated by APG7L/ATG7, transferred to ATG3 and conjugated to phospholipid to form the membrane-bound form, LC3-II. SIMILARITY: Belongs to the MAP1 LC3 family.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Lysates are guaranteed for 6 months from date of receipt.

Bioinformatics

• Gene Symbol: MAP1LC3C