LC3C Products

Antibodies
LC3C Antibody
LC3C Antibody
NBP2-57604
Species: Hu
Applications: ICC/IF
Host: Rabbit Polyclonal
Lysates
LC3C Overexpression Lysate (D ...
LC3C Overexpression Lysate (Denatu...
H00440738-T01
Species: Hu
Applications: WB
Proteins
Recombinant Human LC3C Protei ...
Recombinant Human LC3C Protein
H00440738-P01
Species: Hu
Applications: WB, ELISA, PA
LC3C Recombinant Protein Anti ...
LC3C Recombinant Protein Antigen
NBP2-57604PEP
Species: Hu
Applications: AC

Description

FUNCTION: Probably involved in formation of autophagosomal vacuoles (autophagosomes). SUBUNIT: 3 different light chains, LC1, LC2 and LC3, can associate with MAP1A and MAP1B proteins. SUBCELLULAR LOCATION: LC3-I: Cytoplasm. LC3-II: Intracytoplasmic membrane; lipid-anchor. LC3-II binds to the autophagic membranes. TISSUE SPECIFICITY: Most abundant in placenta, lung and ovary. PTM: The precursor molecule is cleaved by APG4B/ATG4B to form the cytosolic form, LC3-I. This is activated by APG7L/ATG7, transferred to ATG3 and conjugated to phospholipid to form the membrane-bound form, LC3-II. SIMILARITY: Belongs to the MAP1 LC3 family.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Product By Gene ID 440738
Alternate Names
  • MAP1A/MAP1B LC3 C
  • microtubule-associated proteins 1A/1B light chain 3C
  • MAP1 light chain 3-like protein 3
  • MAP1 light chain 3-like protein 2
  • Autophagy-related ubiquitin-like modifier LC3 C
  • LC3-like protein 2
  • Autophagy-related protein LC3 C
  • LC3C
  • ATG8J
  • microtubule-associated protein 1 light chain 3 gammaMAP1A/MAP1B light chain 3 C

Pathways for LC3C

View related products by pathway and learn more about each of the pathways below.

Autophagy
Cell Death
Cell Growth
Rna Interference
Conjugation
Localization

Research Areas for LC3C

Find related products by research area and learn more about each of the different research areas below.

Autophagy
Cellular Markers
Phospho-Specific

PTMs for LC3C

Learn more about PTMs related to LC3C.

Cleavage
Phosphorylation
Ubiquitination

Bioinformatics Tool for LC3C

Discover related pathways, diseases and genes to LC3C. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.

Related LC3C Blog Posts

Check out the latest blog posts on LC3C.
Analyzing LC3 in Western blot
Microtubule-associated protein light chain 3 (LC3) is considered one of the definitive markers of autophagy, and its use is widespread in labs throughout the world. Despite its popularity, there are several considerations when employing LC3 antibodies...    Read more.
Marking the Autophagosome: the LC3 Antibody
MAP1LC3 (shortened to LC3 in our antibody catalog) is one of four mammalian homologues of autophagy-related protein 8 (Atg8). It has been identified as a light chain subunit of the microtubule-associated proteins MAP1A/MAP1B. A modified form of LC3, L...    Read more.
Read more LC3C related blogs.