LASS2 Antibody (B3-2)

Western Blot: LASS2 Antibody (B3-2) [NBP2-66930] - Analysis of LASS2 in on hybrid fish (crucian-carp) brain tissue lysate using anti-LASS2 antibody at 1/500 dilution.

Immunocytochemistry/Immunofluorescence: LASS2 Antibody (B3-2) [NBP2-66930] - Staining LASS2 (red) in K562 cells. Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

Immunohistochemistry-Paraffin: LASS2 Antibody (B3-2) [NBP2-66930] - Analysis of paraffin-embedded human brain tissue using anti-LASS2 antibody. Counter stained with hematoxylin.

Western Blot: LASS2 Antibody (B3-2) [NBP2-66930] - Analysis on K562-AO2 cell lysate using anti-lass2 monoclonal antibody.

Product Discontinued

LASS2 Antibody (B3-2) Summary

• Immunogen: Synthetic peptide within Human LASS2 aa 331-380 / 380. (SwissProt: Q96G23 Human)
• Localization: Nuclear membrane
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Gene: CERS2
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry-Paraffin
  • Western Blot 1:500-1:1000

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH7.4), 0.2% BSA, 40% Glycerol
• Preservative: 0.05% Sodium Azide
• Concentration: 2 mg/ml
• Purity: Protein A purified

Alternate Names for LASS2 Antibody (B3-2)

• ceramide synthase 2
• CerS2
• LAG1 homolog, ceramide synthase 2
• LAG1 longevity assurance 2
• LAG1 longevity assurance homolog 2 (S. cerevisiae)
• LAG1 longevity assurance homolog 2
• S. cerevisiae) homolog 2
• SP260MGC987
• TMSG1
• Tumor metastasis-suppressor gene 1 protein

Background

LASS2 encodes a protein that has sequence similarity to yeast longevity assurance gene 1. Mutation or overexpression of the related gene in yeast has been shown to alter yeast lifespan. The human protein may play a role in the regulation of cell growth. Alternatively spliced transcript variants encoding the same protein have been described.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CERS2