Kv7.1 Antibody (5E12)

Western Blot: Kv7.1 Antibody (5E12) [NBP2-37538] - Western blot analysis using KCNQ1 mouse mAb against MCF-7 (1) and A431 (2) cell lysate.

Flow Cytometry: Kv7.1 Antibody (5E12) [NBP2-37538] - Flow cytometric analysis of MCF-7 cells using KCNQ1 mouse mAb (green) and negative control (red).

Western Blot: Kv7.1 Antibody (5E12) [NBP2-37538] - Western blot analysis using KCNQ1 mAb against human KCNQ1 (AA: 229-347) recombinant protein. (Expected MW is 74.7 kDa)

ELISA: Kv7.1 Antibody (5E12) [NBP2-37538] - Red: Control Antigen (100ng); Purple: Antigen (10ng); Green: Antigen (50ng); Blue: Antigen (100ng);

• Reactivity: Hu
• Applications: WB, ELISA, Flow
• Clone: 5E12
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated

Kv7.1 Antibody (5E12) Summary

• Description: Novus Biologicals Mouse Kv7.1 Antibody (5E12) (NBP2-37538) is a monoclonal antibody validated for use in WB, ELISA and Flow. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Purified recombinant fragment of human Kv7.1 expressed in E. Coli.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Gene: KCNQ1
• Purity: Unpurified

Applications/Dilutions

• Dilutions:
  • ELISA 1:10000
  • Flow Cytometry 1:200 - 1:400
  • Western Blot 1:500 - 1:2000
• Theoretical MW: 95 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: Ascites
• Preservative: 0.03% Sodium Azide
• Purity: Unpurified

Alternate Names for Kv7.1 Antibody (5E12)

• ATFB3
• IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1
• JLNS1
• KCNA8
• KCNA8FLJ26167
• KCNA9
• KCNA9Kv1.9
• KCNQ1
• kidney and cardiac voltage dependend K+ channel
• KQT-like 1
• Kv7.1
• KVLQT1
• KVLQT1ATFB1
• LQT
• LQT1
• potassium voltage-gated channel subfamily KQT member 1
• potassium voltage-gated channel, KQT-like subfamily, member 1
• RWS
• slow delayed rectifier channel subunit
• SQT2
• Voltage-gated potassium channel subunit Kv7.1
• WRS

Background

KCNQ1 encodes a protein for a voltage-gated potassium channel required for the repolarization phase of the cardiac action potential. The gene product can form heteromultimers with two other potassium channel proteins, KCNE1 and KCNE3. Mutations in this gene are associated with hereditary long QT syndrome, Romano-Ward syndrome, Jervell and Lange-Nielsen syndrome and familial atrial fibrillation. The gene is located in a region of chromosome 11 that contains a large number of contiguous genes that are abnormally imprinted in cancer and the Beckwith-Wiedemann syndrome. Two alternative transcripts encoding distinct isoforms have been described (from EntrezGene).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: KCNQ1