KMT2B Antibody (4C10)

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Sandwich ELISA: KMT2B Antibody (4C10) [H00009757-M02] - Detection limit for recombinant GST tagged MLL4 is approximately 0.03ng/ml as a capture antibody.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA
Clone
4C10
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

KMT2B Antibody (4C10) Summary

Immunogen
MLL4 (NP_055542, 813 a.a. ~ 905 a.a) partial recombinant protein with GST tag.KVAASMPLSPGGQMEEVAGAVKQISDRGPVRSEDESVEAKRERPSGPESPVQGPRIKHVCRHAAVALGQARAMVPEDVPRLSALPLRDRQDL
Specificity
MLL4 - myeloid/lymphoid or mixed-lineage leukemia 4
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
MLL4
Purity
IgG purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500
  • ELISA
Application Notes
Antibody reactive against recombinant protein with GST tag on ELISA and Western Blot. GST tag alone is used as a negative control.

Reactivity Notes

Human. Other species not tested.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.4)
Preservative
No Preservative
Purity
IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for KMT2B Antibody (4C10)

  • EC 2.1.1.43
  • histone-lysine N-methyltransferase MLL4
  • HRX2
  • KIAA0304WW domain-binding protein 7
  • Lysine N-methyltransferase 2D
  • mixed lineage leukemia gene homolog 2
  • MLL2
  • myeloid/lymphoid or mixed-lineage leukemia 4
  • Myeloid/lymphoid or mixed-lineage leukemia protein 4
  • Trithorax homolog 2
  • trithorax homologue 2
  • TRX2
  • WBP7
  • WBP-7
  • WW domain binding protein 7

Background

This gene encodes a protein which contains multiple domains including a CXXC zinc finger, three PHD zinc fingers, two FY-rich domains, and a SET (suppressor of variegation, enhancer of zeste, and trithorax) domain. The SET domain is a conserved C-terminal domain that characterizes proteins of the MLL (mixed-lineage leukemia) family. This gene is ubiquitously expressed in adult tissues. It is also amplified in solid tumor cell lines, and may be involved in human cancer. Two alternatively spliced transcript variants encoding distinct isoforms have been reported for this gene, however, the full length nature of the shorter transcript is not known.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

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Secondary Antibodies

 

Isotype Controls

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KMT2B H00009757-M02

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Bioinformatics

Gene Symbol MLL4
Entrez
OMIM
Uniprot