Recombinant Human KLF3 His Protein

SDS-Page: KLF3 Protein [NBP2-23175]

• Reactivity: Hu
• Applications: PAGE
• Concentration: 1 mg/ml

Recombinant Human KLF3 His Protein Summary

• Description: A denatured recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-345 of Human KLF3
  
  

  Source: E.coli

  Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGSMLMFDPV PVKQEAMDPV SVSYPSNYME SMKPNKYGVI YSTPLPEKFF QTPEGLSHGI QMEPVDLTVN KRSSPPSAGN SPSSLKFPSS HRRASPGLSM PSSSPPIKKY SPPSPGVQPF GVPLSMPPVM AAALSRHGIR SPGILPVIQP VVVQPVPFMY TSHLQQPLMV SLSEEMENSS SSMQVPVIES YEKPISQKKI KIEPGIEPQR TDYYPEEMSP PLMNSVSPPQ ALLQENHPSV IVQPGKRPLP VESPDTQRKR RIHRCDYDGC NKVYTKSSHL KAHRRTHTGE KPYKCTWEGC TWKFARSDEL TRHFRKHTGI KPFQCPDCDR SFSRSDHLAL HRKRHMLV

• Source: E. coli
• Protein/Peptide Type: Recombinant Protein
• Gene: KLF3
• Purity: >90%, by SDS-PAGE

Applications/Dilutions

• Dilutions:
  • SDS-Page
• Application Notes: Denatured protein is most likely not the best option for functional studies. It is better suited for Western Blot (WB) or imaging assays.
• Theoretical MW: 41.2 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 20 mM Tris-HCl buffer (pH 8.0), 0.4M UREA, 10% glycerol
• Preservative: No Preservative
• Concentration: 1 mg/ml
• Purity: >90%, by SDS-PAGE

Alternate Names for Recombinant Human KLF3 His Protein

• Basic krueppel-like factor
• basic Kruppel-like factor
• BKLFbasic kruppel like factor
• CACCC-box-binding protein BKLF
• Krueppel-like factor 3
• Kruppel-like factor 3 (basic)
• MGC48279
• TEF-2

Background

Krueppel-like factor3, also known as KLF3, is a member of the Sp1-like/KLF family. Kruppel-like factors (KLFs) comprise a family of evolutionarily conserved zinc finger-containing transcription factors with diverse regulatory functions in cell growth, proliferation, differentiation and embryogenesis. KLF3 is Kruppel-like zinc finger containing transcription factors. KLF3 may play a role in hematopoiesis. Recombinant human KLF3 protein, fused to His-tag at N-terminus, was expressed in E.coli.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Publications for KLF3 Protein (NBP2-23175)(1)

Publication using NBP2-23175

• Yang M, Guo Q, Peng H et al. Kruppel-like factor 3 inhibition by mutated lncRNA Reg1cp results in human high bone mass syndrome J. Exp. Med. 2019-06-13 [PMID: 31196982]

Bioinformatics

• Gene Symbol: KLF3