KLF11 Antibody (RB19899)

Product Discontinued

KLF11 Antibody (RB19899) Summary

• Immunogen: This TIEG2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 7-36 amino acids from the N-terminal region of human TIEG2.
• Localization: Cellular Location Nucleus. Tissue Location Ubiquitous. Higher expression in erythroid cells
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: KLF11
• Purity: Ammonium sulfate precipitation

Applications/Dilutions

• Dilutions:
  • Flow Cytometry 1:10 - 1:50
  • Immunocytochemistry/ Immunofluorescence 1:10 - 1:50
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 1:50 - 1:100
  • Western Blot 1:1000
• Theoretical MW: 55.139 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Predicted to react with Mouse.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.09% Sodium Azide
• Concentration: 6.88 mg/ml
• Purity: Ammonium sulfate precipitation

Alternate Names for KLF11 Antibody (RB19899)

• FKLFFKLF1
• Krueppel-like factor 11
• Kruppel-like factor 11
• MODY7TGFB-inducible early growth response protein 2
• TIEG-2
• TIEG2TGFB inducible early growth response 2
• Tieg3
• Transforming growth factor-beta-inducible early growth response protein 2

Background

TIEG2 is a transcription factor. The protein activates the epsilon- and gamma-globin gene promoters and, to a much lower degree, the beta-globin gene and represses promoters containing SP1-like binding inhibiting cell growth. It represses transcription of SMAD7 which enhances TGF-beta signaling. It induces apoptosis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for KLF11 Antibody (NBP2-30072)(1)

Publication using NBP2-30072

• Kim S, Koh J, Kim MY et al. PD-L1 expression is associated with epithelial-to-mesenchymal transition in adenocarcinoma of the lung Hum. Pathol. 2016-07-26 [PMID: 27473266] (WB, Human)

Bioinformatics

• Gene Symbol: KLF11
• Uniprot:
  • O14901(Human)