KIR2DS5/CD158g Antibody (1165A) [Phycoerythrin]

• Applications: Flow
• Clone: 1165A
• Clonality: Monoclonal
• Host: Rabbit
• Conjugate: Phycoerythrin

KIR2DS5/CD158g Antibody (1165A) [Phycoerythrin] Summary

• Additional Information: Recombinant Monoclonal Antibody
• Immunogen: NS0 mouse myeloma cell line transfected with human KIR2DS5/CD158g
  His22-His245
  Accession # Q14953
• Specificity: Detects human KIR2DS5/CD158g in direct ELISAs.
• Source: N/A
• Isotype: IgG
• Clonality: Monoclonal
• Host: Rabbit
• Purity Statement: Protein A or G purified from cell culture supernatant

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.
• Buffer: Supplied in a saline solution containing BSA and Sodium Azide.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Background

Killer-immunoglobulin-like receptors (KIR) are polymorphous activating and inhibitory receptors expressed on the surface of NK cells and some T cells. KIR genes are highly homologous. KIR proteins expressing the long (L) cytoplasmic domain are inhibitory, while KIRs with short (S) cytoplasmic domains are activating. Thus, KIR2DS5 is an activating receptor for NK cells, and is thought to play a role in NK cell function in response to a number of conditions. While many KIR proteins bind HLA-class I molecules, the ligand(s) for KIR2DS5 remain unknown.  

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.