KIR2DS5/CD158g Products

Antibodies
KIR2DS5/CD158g Antibody (1165 ...
KIR2DS5/CD158g Antibody (1165A) [U...
MAB8920
Species: Hu
Applications: Flow
Host: Rabbit Monoclonal
Conjugate Catalog # Availability Size Price
Lysates
KIR2DS5/CD158g Overexpression ...
KIR2DS5/CD158g Overexpression Lysa...
NBP2-07322
Applications: WB
RNAi
KIR2DS5/CD158g RNAi
KIR2DS5/CD158g RNAi
H00003810-R02
Species: Hu
Applications: RNAi, RNAi SP

Description

Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several "framework" genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules; thus, KIR proteins are thought to play an important role in regulation of the immune response. (provided by RefSeq)

Bioinformatics

Entrez Human
Uniprot Human
Product By Gene ID 3810
Alternate Names
  • killer cell immunoglobulin-like receptor 2DS5
  • CD158G
  • NKAT9
  • killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 5

Pathways for KIR2DS5/CD158g

View related products by pathway and learn more about each of the pathways below.

Pathogenesis
Immune Response
Aging
Donor Selection

PTMs for KIR2DS5/CD158g

Learn more about PTMs related to KIR2DS5/CD158g.

Biotinylation
Deglycosylation

Bioinformatics Tool for KIR2DS5/CD158g

Discover related pathways, diseases and genes to KIR2DS5/CD158g. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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